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cDNAs and proteins involved in hypoxia, circadian and orphan signal transduction pathways, and methods of use
cDNAs and proteins involved in hypoxia, circadian and orphan signal transduction pathways, and methods of use
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机译:涉及缺氧,昼夜节律和孤儿信号转导途径的cDNA和蛋白质及其使用方法
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摘要
The present invention provides isolated nucleic acids and proteins that are new and distinct members of the bHLH-PAS superfamily of transcription regulators. These “MOPs” (members of PAS) are useful in a variety of research, diagnostic and therapeutic applications. Several of the MOPs of the present invention are α-class hypoxia-inducible factors. Several other of the MOPs of the invention are involved in circadian signal transduction.
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