METHOD FOR INCREASING URINARY BLADDER VOLUME AFTER HAVING DONE SUBTOTAL RESECTION IN THE CASES OF LOCALLY EXTENDED COLORECTAL CANCER

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• 2. 使用磁性微粒将分析物从大体积浓缩至较小体积中的DMF方法和系统 [P] . 中国专利： CN109073518A . 2018-12-21
• 3. METHOD FOR DETECTING THE VOLUME OF URINARY BLADDER RESECTION AT ENDOSCOPIC THERAPY OF URINARY BLADDER CANCER [P] . 俄罗斯专利： RU2317009C1 . 2008-02-20

  机译： 膀胱癌内镜治疗中检测膀胱切除体积的方法

• 4. METHOD OF TRANSURETHRAL RESECTION OF URINARY BLADDER WALL WITH URETERAL ORIFICE WITH APPLICATION OF TULIUM FIBER LASER IN LAPAROSCOPIC NEPHROURETERECTOMY FOR TREATMENT OF PATIENTS WITH HIGH URINARY CANCER OF HIGH DEGREE OF MALIGNANCY [P] . 俄罗斯专利： RU2716349C1 . 2020-03-11

  机译： 输尿管镜行尿道膀胱尿道穿刺切除术的应用WITH纤维激光在腹腔镜肾输尿管镜术中治疗高尿酸度高恶性肿瘤的患者

• 5. METHOD FOR RECONSTRUCTING URINARY BLADDER AFTER RESECTION OF CANCER INVADING BLADDER AND PROSTATE [P] . UA39522U . 2009-02-25

  机译： 前列腺癌切除术后尿膀胱重建方法

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• 1. BACKGROUND： Vibrio vulnifi cus inside the body could activate the NF-!B signaling pathwayand initiate the inflammatory cascade. The lung is one of the earliest organs affected by sepsisassociated with acute lung injury. High mobility group protein B1 （HMGB1） is an important late-actingpro-infl ammatory cytokine involving in the pathophysiology of sepsis. It is also involved in the injuryprocess in the lung, liver and intestine. There has been no report on the involvement of HMGB1 inVibrio vulnifi cus sepsis-induced lung injury.METHODS： Sixty rats were randomly divided into a normal control group （group A, n=10） anda Vibrio vulnificus sepsis group （group B, n=50）. Sepsis was induced in the rats by subcutaneousinjection of Vibrio vulnificus （concentration 6×108 cfu/mL, volume 0.1 mL/100g）） into the left lowerlimbs. The rats in group B were sacrifi ced separately 1, 6, 12, 24, and 48 hours after the infection.Their lungs were stored as specimens, lung water content was measured, and lung pathology wasobserved under a light microscope. The expressions of the HMGB1 gene and protein in the lungswere detected by RT-PCR and Western blot. Data were analyzed with one-way analysis of variance（ANOVA） and the LSD method for pair-wise comparison between the two groups. P〈0.05 wasconsidered statistically signifi cant.RESULTS： Compared to group A （0.652±0.177）, HMGB1 mRNA expression in the lungs ofgroup B was signifi cantly higher at 0 hour （1.161±0.358, P=0.013）, 24 hours （1.679±0.235, P=0.000）,and 48 hours （1.258±0.274, P=0.004） （P〈0.05）, and peaked at 24 hours. Compared to group A（0.594±0.190）, HMGB1 protein expression at 6 hours （1.408±0.567, P=0.026） after infection wassignificantly increased （P〈0. 05）, and peaked at 24 hours （2.415±1.064, P=0.000） after infection.Compared to group A （0.699±0.054）, lung water content was significantly increased at 6 hours（0.759±0.030, P=0.001）,12 hours （0.767±0.023, P=0.000）, 24 hours （0.771±0.043, P=0.000） and 48hours （0.789±0.137, P=0.000） after infection （P〈0.05）. Compared to group A, pathological changesat 12 hours in group B indicate marked pulmonary vascular congestion, interstitial edema andinfl ammatory infi ltration. Alveolar cavity collapse and boundaries of the alveolar septum could not beclearly identifi ed.CONCLUSION： Vibrio vulnifi cus sepsis can lead to injury in rat lungs, and increased HMGB1expression in lung tissue may be one of the mechanisms for injury from Vibrio vulnifi cus sepsis. [J] . Qiao-meng Qiu ,Zhong-wang Li ,Lu-ming Tang . 世界急诊医学杂志(英文) . 2011,第4期
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