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Heteromorphic carbohydrates concentrated as purchasing power parity painkillers
Heteromorphic carbohydrates concentrated as purchasing power parity painkillers
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机译:异质碳水化合物集中作为购买力平价止痛药
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摘要
It refers to formula compound (I),Where AR is ring mequillo (C3-C10),Isopropyl (C2-C10),Arilo(C6-C10),Or alien (C1-C10),Where r can be replaced by 1 to 4 Z substitutes; a is - CH2 -.- en -O-O-SR1 is a tar (C1-C8),Cyclopropyl (C3-C10),Isopropyl (C2-C10),Arilo (C6-C10) or heterosexual (C1-C10),Can be replaced by one to four Z1 substitutes; and is - (CH2) n -,-(CH2)N-N15---(CH2)N-OY-(CH2)N-S-;This is.-(CR2R3)M-N15-,-N15-(CR2R3)M--Het is a condensed heteromorphic compound (C6-C12), which can be replaced by 1-4 of Z3, in which Z3 may exist in any heteromorphic ring; t is - (C = O) - OH - (C = O) - or15 - (C = O) - om -.(where m is an alkaline metal or alkaline earth metal)Tetrazolilo,tiazolidinio,so2-nh-r15,entre otros. The most popular compounds are: acid 3 - {4 - {2 - (5-methyl-2-phenyl-1,3-oxazol-4-il) etoxi] - 1h-indazol-1-il} propane, acid 4 - {4 - [2 - (5-methyl-2-phenyl-1,3-oxazol-4-il) etoxi] - 2h-indazol-2-il} butane, etc. He also mentioned a pharmacology composer who included it These compounds are acute activities of par active receptors and are useful in blood glucose modulation and in increasing insulin sensitivity, so they have been documented in the treatment of diabetes, defatting, obesity and flammability.
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机译:它是指式(I)的化合物,其中AR是环甲氧基(C3-C10),异丙基(C2-C10),阿里洛(C6-C10)或外来物(C1-C10),其中r可以替换为1至4个Z替代物; a是-CH2 -.- en -OO-SR1是焦油(C1-C8),环丙基(C3-C10),异丙基(C2-C10),阿里洛(C6-C10)或异性(C1-C10),可以被一到四个Z1替代物替代;并且是-(CH2)n-,-(CH2)N-N15 ---(CH2)N-OY-(CH2)NS-;这是-(CR2R3)M-N15-,-N15-(CR2R3) M-Het是稠合的多晶化合物(C6-C12),可以被Z3的1-4取代,其中Z3可以存在于任何多晶环中; t是-(C = O)-OH-(C = O)-或15-(C = O)-om-。(其中m为碱金属或碱土金属)替他唑利洛,噻唑烷,so2-nh-r15, entre otros。最受欢迎的化合物为:酸3-{4-{2-(5-甲基-2-苯基-1,3-恶唑4-il)依托昔]]-1h-吲哚-1-il}丙烷,酸4- {4-[2-(2-(5-甲基-2-苯基-1,3-恶唑-4-il)依托昔]]-2h-吲哚-2-il}丁烷等。他还提到了将其包括在内的药理作曲家。这些化合物具有同种活性受体的急性活性,可用于血糖调节和提高胰岛素敏感性,因此已在糖尿病,脱脂,肥胖和可燃性的治疗中得到记录。
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