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Simple and rapid derivation of functional hepatocytes from human bone marrow-derived mesenchymal stem cells

机译:从人骨髓间充质干细胞简单快速地获得功能性肝细胞

摘要

This disclosure provides methods for preparing hepatocytes from mesenchymal stem cells by culturing in a first culture media comprising hepatocyte growth factor and a second culture media comprising oncostatin-M. The disclosure also provides the MSC-derived hepatocytes produced by these methods and both in vivo and in vitro uses for these MSC-derived hepatocytes.
机译:本公开提供了通过在包含肝细胞生长因子的第一培养基和包含制瘤素-M的第二培养基中培养从间充质干细胞制备肝细胞的方法。本公开还提供了通过这些方法产生的MSC来源的肝细胞,以及这些MSC来源的肝细胞的体内和体外用途。

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