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Highly purified mocarhagin, a cobra venom protease, polynucleotides encoding same and related proteases, and therapeutic uses thereof

机译:高度纯化的莫卡那丁,眼镜蛇毒蛋白酶,编码相同和相关蛋白酶的多核苷酸及其治疗用途

摘要

Methods and compositions for treating a wide range of inflammatory diseases and disorders, and for inhibiting selectin-mediated binding by administering a mocarhagin protein, or fragments thereof with mocarhagin protein activity are provided. The mocarhagin protein may be administered alone, or in combination with a cytokine, lymphokine, or hematopoietic factor.
机译:本发明提供了用于治疗多种炎性疾病和病症以及通过施用莫卡金蛋白或其具有莫卡金蛋白活性的片段来抑制选择蛋白介导的结合的方法和组合物。 Mocarhagin蛋白可以单独给药,也可以与细胞因子,淋巴因子或造血因子联合给药。

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