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METHODS FOR IDENTIFYING COMPOUNDS THAT MODULATE DISORDERS RELATED TO NITRIC OXIDE/CGMP-DEPENDENT PROTEIN KINASE SIGNALING
METHODS FOR IDENTIFYING COMPOUNDS THAT MODULATE DISORDERS RELATED TO NITRIC OXIDE/CGMP-DEPENDENT PROTEIN KINASE SIGNALING
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机译:鉴定与一氧化氮/ CGMP相关蛋白激酶信号转导相关疾病的化合物的方法
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摘要
The invention provides a method of identifying a compound that modulates a disease associated with a nitric oxide/cGMP-dependent protein kinase network in a mammal. The method consists of (a) administering a test compound to an invertebrate; and (b) measuring a foraging behavior of the invertebrate, wherein a compound that modulates the foraging behavior of the invertebrate is characterized as a compound that modulates a disease associated with a nitric oxide/cGMP-dependent protein kinase network in a mammal.
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