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ANALYTICAL PLATFORM AND IDENTIFICATION METHOD WITH ANALYTES, WHICH ARE TO BE IDENTIFIED IN A SAMPLE OPTIONALLY AFTER FRACTIONATION AND WHICH SERVE AS IMMOBILIZED SPECIFIC BINDING PARTNERS
ANALYTICAL PLATFORM AND IDENTIFICATION METHOD WITH ANALYTES, WHICH ARE TO BE IDENTIFIED IN A SAMPLE OPTIONALLY AFTER FRACTIONATION AND WHICH SERVE AS IMMOBILIZED SPECIFIC BINDING PARTNERS
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机译：分馏后需要在样品中鉴定并用作固定特定结合伙伴的分析平台和鉴定方法
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摘要
The invention relates to an analytical platform and a method carried out therewith for examining a plurality of naturally identical samples for biologically relevant compounds taking part in specific binding reactions in the form of analytes, characterized in that said samples or dilutions of said samples, with the analyte to be detected contained therein, are applied without modification of the relative molecular composition in comparison to the original relative molecular composition of the sample, as a first plurality of specific binding partners in at least one one-dimensional or two-dimensional array in discrete measuring areas on an evanescence field sensor platform as a fixed carrier; one or several detection substances are brought into contact in one or more steps of a specific binding reaction with the samples applied in said discrete measuring areas in the form of a second plurality of specific binding partners for specific detection of one or several analytes contained in the sample from said first plurality of specific binding partners; modifications of optoelectronic signals resulting from the binding of detection substances to analytes contained in the samples in the discrete measuring areas are measured with local resolution in the evanescence field of the evanescence field sensor platform and the presence of the analytes which are to be specifically detected is determined quantitatively or qualitatively on the basis of the relative quantity of the modifications of said optoelectronic signals from the respective measuring areas.
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