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5- ANTICANCER DRUG MADE OF CURCUMIN AND 5-FLUOROURACIL AND ITS CLINICAL USES

机译:姜黄素和5-氟尿嘧啶的5-抗癌药及其临床应用

摘要

PURPOSE: An anticancer agent comprising curcumin and 5-fluorouracil having excellent anticancer effect on stomach cancer in capsule form is provided. The agent has a synergistic effect on the treatment of stomach cancer as compared to separate administration of curcumin and 5-fluorouracil. CONSTITUTION: The anticancer agent contains 150 to 800mg curcumin and 100 to 600mg 5-fluorouracil and is orally administered to a cancer patient. The curcumin inhibits proliferation of human stomach cancer cells in contrast to concentrations thereof, the proliferation inhibiting effect thereof is reversible. The concentration(5 to 50M) of the curcumin shows that lower than a serum concentration(2 to 100M) which can be reached by taking 160mg to 8g per a day.
机译:目的:提供包含姜黄素和5-氟尿嘧啶的抗癌剂,其以胶囊形式对胃癌具有优异的抗癌作用。与姜黄素和5-氟尿嘧啶分开给药相比,该药物对胃癌具有协同作用。组成:该抗癌药含有150至800毫克姜黄素和100至600毫克5-氟尿嘧啶,并向癌症患者口服。姜黄素与其浓度相比抑制人胃癌细胞的增殖,其增殖抑制作用是可逆的。姜黄素的浓度(5至50M)显示比每天服用160mg至8g可以达到的血清浓度(2至100M)低。

著录项

  • 公开/公告号KR20030066927A

    专利类型

  • 公开/公告日2003-08-14

    原文格式PDF

  • 申请/专利权人 KOO JA YOUNG;

    申请/专利号KR20020006690

  • 发明设计人 KOO JA YOUNG;

    申请日2002-02-06

  • 分类号A61K31/505;

  • 国家 KR

  • 入库时间 2022-08-21 23:46:24

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