首页> 外国专利> METHOD OF EVALUATING AND IDENTIFYING BIOLOGICALLY FUNCTIONAL MOLECULE USING MARKER GENE

METHOD OF EVALUATING AND IDENTIFYING BIOLOGICALLY FUNCTIONAL MOLECULE USING MARKER GENE

机译:利用MARKER基因评估和鉴定生物功能分子的方法

摘要

It is intended to provide a novel method of screening a biologically active substance with the use of a gene (marker gene) relating specifically to a specific biological phenomenon. It is also intended to provide a gene therefor, a transformant having the gene transferred thereinto, and a kit for detecting, identifying or evaluating a functional molecule containing the same. Namely, a method of screening a functional molecule inducing a specific biological phenomenon with the use of, as an indication, the expression dose of a gene (marker gene) relating specifically to this phenomenon; a gene having a reporter gene fused to the downstream of the promoter of a marker gene; utilization of the gene; a kit for detecting, identifying or evaluating a functional molecule inducing a specific biological phenomenon containing the gene; and cells having been transformed by the gene.
机译:旨在提供一种使用与特定生物学现象特别相关的基因(标记基因)来筛选生物活性物质的新颖方法。还旨在提供用于其的基因,具有导入其中的基因的转化体以及用于检测,鉴定或评估包含该基因的功能分子的试剂盒。即,以与该现象有关的基因(标记基因)的表达量为指标,筛选引起特定生物学现象的功能性分子的方法。具有与标记基因的启动子的下游融合的报告基因的基因;基因的利用;用于检测,鉴定或评估诱导包含该基因的特定生物学现象的功能分子的试剂盒;和已经被该基因转化的细胞。

著录项

  • 公开/公告号WO03035866A1

    专利类型

  • 公开/公告日2003-05-01

    原文格式PDF

  • 申请/专利号WO2002JP08983

  • 发明设计人 SAKAMOTO AIJI;

    申请日2002-09-04

  • 分类号C12N15/09;C12N5/10;C12Q1/68;

  • 国家 WO

  • 入库时间 2022-08-21 23:53:23

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