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A process for the change in the genome of gram - positive bacteria with a new negative dominant marker gene

机译:用新的负显性标记基因改变革兰氏阳性细菌基因组的过程

摘要

The invention relates to a novel method of modifying the genome of gram-positive bacteria, to said bacteria and to novel vectors. The invention especially relates to a method of modifying iCorynebacteria/i or iBrevibacteria/i using a novel marker gene that has a conditionally negative dominant effect.
机译:本发明涉及修饰革兰氏阳性细菌的基因组的新方法,所述细菌和新型载体。本发明尤其涉及使用具有条件性负显性作用的新型标记基因修饰棒状杆菌或短杆菌的方法。

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