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One chain DNA or two these chains DNA, development of the encoding fusion protein, the virus and the virus which withstands the packaging cell and the non- life conversion which is by these employee assistant body systems
One chain DNA or two these chains DNA, development of the encoding fusion protein, the virus and the virus which withstands the packaging cell and the non- life conversion which is by these employee assistant body systems
(57) Abstract The mouse retro-virus confronts human gene remedy, it is the most important transmission system. But, at present there is a limit in the application. As for one among main restrictions when it applies to in vivo, you can list the problem that it is the point which is sensitive to the non- life conversion where the virus of this type is by the assistant body factor of the person. This invention overcomes this restriction. These inventors decorated, in order the mouse rearrangement retro-virus, those for there to be a resistance vis-a-vis human assistant body factor. This was achieved by the gene decoration of surface protein env of the retro-virus which becomes cause of receptor interaction. It made fuse the territory of the receptor interaction of env, depending upon the active region and catalytic action of assistant body non- life conversion factor of the person. This env which is decorated is revealed in the cell which is sensitive to the assistant body is installed in the virus particle uniquely. You can obtain the cell and the virus which can be resisted sufficiently with this method, vis-a-vis the invasion of the assistant body. Therefore, as for this method the expedient for the production of the virus of establishment of the assistant body resistant sex cell in the gene medical therapy in the organism is offered.
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