首页>
外国专利>
Derivatives of polyketides, isolated polynucleotides sequence, or a fragment thereof, a Vector, a host Cell,And a method to alter the substrate specificity of a polyketide synthase in a First micro organism producing polyketide
Derivatives of polyketides, isolated polynucleotides sequence, or a fragment thereof, a Vector, a host Cell,And a method to alter the substrate specificity of a polyketide synthase in a First micro organism producing polyketide
A polymetallic derivative consisting of formula (I), wherein R1, R2, R3, R4, R5 and R6 are independently selected,In Q, they were selected from the following groups: (a) - (H) (b) - (me) (c) - (ET) and (d) - (OH); R7 was selected from the ET home (hydroxy) group:There are also 3,4-dihydroxycyclopentanediol; L1 and L2 are independent of each other - h-u-oh; L3 is d-dessamina u-oh; L4 is l-microsa, l-claudiosa - Oh, provided that if R7 is ET and R1-R5 is - me, RG is different from - h-me. Reagents such as insulated polynucleotide, vehicles including polynucleotide and host cells modified by vehicles are also provided to prepare for new discoveries. In addition, the method of using genetic engineering technology to produce compounds is introduced.
展开▼
