首页> 外国专利> Cells expressing a substantial number of surface high affinity HBGF receptors but relatively few low affinity HBGF binding sites and system for assaying binding to HBGF receptor

Cells expressing a substantial number of surface high affinity HBGF receptors but relatively few low affinity HBGF binding sites and system for assaying binding to HBGF receptor

机译:表达大量表面高亲和力HBGF受体但相对较少的低亲和力HBGF结合位点的细胞和用于分析与HBGF受体结合的系统

摘要

A homogeneous population of cells having on average (1) a number of cell surface low-affinity heparin-binding growth factor (HBGF) sites per cell less than 20% of the number of such binding sites found on wild-type CHO-K1 cells (ATCC Accession No. CCL61), and at least three times the number of cell surface high-affinity HBGF receptors per cell found on such CHO-K1 cells; and an assay system utilizing such cells.
机译:每个细胞平均具有(1)个细胞表面低亲和力肝素结合生长因子(HBGF)位点的均质细胞群,其数量少于野生型CHO-K1细胞中此类结合位点数的20% (ATCC登录号CCL61),并且至少是这种CHO-K1细胞上每个细胞的细胞表面高亲和力HBGF受体数量的三倍;以及使用这种细胞的测定系统。

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