首页> 外国专利> NOVEL DERIVATIVES OF 1-(2-,3- OR 4-QUINOLYL)- 2-OR -3-(2- OR 3-PIPERIDYL OR -PYRROLIDINYL) ETHANONE OR PROPANONE, MANUFACTURE AND MEDICINE USING SAME

NOVEL DERIVATIVES OF 1-(2-,3- OR 4-QUINOLYL)- 2-OR -3-(2- OR 3-PIPERIDYL OR -PYRROLIDINYL) ETHANONE OR PROPANONE, MANUFACTURE AND MEDICINE USING SAME

机译:1-(2-,3-或4-喹啉)-2-或-3-(2-或3-哌啶基或-吡咯烷基)乙酮或丙烷的新衍生物,使用相同的制备方法和药物

摘要

Compounds, useful as medicaments, of the formula: IMAGE (I) in which R is fixed in position 2 or 4 on the cycle of the quinoline and indicates a hydrogen atom or an alkyl group containing 1 to 4 carbon atoms, pyridyl, thienyl, phenyl or substituted phenyl group, X is fixed in position 5, 6, 7 or 8 on the cycle of the quinoline and indicates a hydrogen or halogen atom or an alkyl, alkoxy or alkylthio group containing 1 to 4 carbon atoms or CF3 group, R1 is a hydrogen atom or an alkyl containing 1 to 4 carbon atoms, alkenyl containing 3 to 4 carbon atoms or arylalkyl group, A is a CO, CHOH, or CH2 group, n and p are equal to 1 or 2, the group IMAGE is fixed in position 2, 3 or 4 on the cycle of the quinoline and the group IMAGE is fixed in position 2 or 3 on the nitrogen heterocycle IMAGE
机译:式中用作药物的化合物:[IMAGE](I),其中R固定在喹啉环的2或4位上,表示氢原子或含1-4个碳原子的烷基,吡啶基,噻吩基,苯基或取代的苯基,X固定在喹啉的环的5、6、7或8位上,表示氢或卤素原子或含1-4个碳原子的烷基,烷氧基或烷硫基或CF3基团,R 1是氢原子或含1-4个碳原子的烷基,含3-4个碳原子的烯基或芳基烷基,A是CO,CHOH或CH 2基,n和p等于1或2,该基团固定在喹啉循环的2、3或4位,组固定在氮杂环的2或3位。

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