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Sieve Low Substitution Hydroxypropyl Cellulose Production Method
Sieve Low Substitution Hydroxypropyl Cellulose Production Method
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机译:筛床低替代羟丙基纤维素生产方法
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摘要
PROBLEM TO BE SOLVED: To provide a method for producing a sieved L-HPC having an improved yield while maintaining the fluidity of hydroxypropyl cellulose (L-HPC) having a low degree of sieving and the tablet characteristics after tableting. SOLUTION: L-HPC having a hydroxypropoxy group content of 5 to 16% by mass is sieved using a sieve shaker in which the sieve surface moves horizontally to obtain a first residual L-HPC on the sieve. , The first sieving step of obtaining the first sieve-passing L-HPC and the second sieving of the residual L-HPC on the first sieve using a sieve shaker in which the sieving surface moves vertically. The second sieving step of obtaining the residual L-HPC on the sieve and the second L-HPC passing through the sieve, and the sieving L by combining the L-HPC passing through the first sieve and the residual L-HPC on the second sieve. Provided is a method for producing a sieved L-HPC, which comprises at least a mixing step for obtaining −HPC. [Selection diagram] None
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