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COMPOSITIONS AND METHODS FOR IN VITRO ACTIVATION AND EXPANSION OF SERIAL KILLER T CELL POPULATIONS AND PASSIVE IMMUNIZATION OF A CANCER PATIENT WITH TUMOR CELL KILLING CELLS
COMPOSITIONS AND METHODS FOR IN VITRO ACTIVATION AND EXPANSION OF SERIAL KILLER T CELL POPULATIONS AND PASSIVE IMMUNIZATION OF A CANCER PATIENT WITH TUMOR CELL KILLING CELLS
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机译：用于体外活化和扩展连续杀伤T细胞群的组合物和方法，肿瘤细胞杀伤细胞的癌症患者的被动免疫
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摘要
The described invention provides a method for in vitro immunoactivation of mononuclear cells by contact with one or more populations of engineered leukocyte stimulator cells genetically engineered to express a core of 3 essential immunomodulator peptides, and optionally additional R immunomodulator peptides, and use of a cell product comprising the expanded and activated mononuclear cell population comprising one or more subpopulations of cytotoxic serial killer cells for passive immunization of a cancer patient not currently under the influence of an immunosuppressive regimen.
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