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MCF-7 MCF-7 cell line having anticancer drug resistance and method for preparing same
MCF-7 MCF-7 cell line having anticancer drug resistance and method for preparing same
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机译:MCF-7 MCF-7细胞系具有抗癌耐药性和制备方法
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摘要
To an MCF-7 cell line having anticancer drug resistance and a method for preparing the same, the method comprising: administering a CDK4/6 inhibitor to a mouse transplanted with the MCF-7 cell line; and separating resistant cells that have acquired resistance to the CDK4/6 inhibitor from the tumor tissue of the MCF-7 cell line transplanted mouse administered with the CDK4/6 inhibitor; a method for producing a CDK4/6 inhibitor-resistant cell line comprising a; , It provides a composition for screening a cancer therapeutic agent comprising a CDK4/6 inhibitor-resistant cell line prepared by the above method, and a screening method.
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