首页> 外国专利> HA HA Design for recombinant protein for influenza virus surface protein hemagglutinin a method of mass-production of its in plants and pharmaceutical composition for treating and preventing influenza virus containing its

HA HA Design for recombinant protein for influenza virus surface protein hemagglutinin a method of mass-production of its in plants and pharmaceutical composition for treating and preventing influenza virus containing its

机译:用于流感病毒表面蛋白血凝素的重组蛋白的HA HA设计血凝素的植物和药物组合物的批量生产方法,用于治疗和预防含有其流感病毒

摘要

The present invention relates to a method for designing a recombinant hemagglutinin (HA) protein gene derived from an influenza virus surface protein that forms a trimer, and a method for mass-producing the recombinant HA protein in a plant. Specifically, immunogenicity enhancement and effective antigen A method for designing a recombinant gene capable of trimerizing a recombinant hemagglutinin (HA) protein derived from an influenza virus surface protein for the purpose of delivery, a method for mass production of the HA recombinant protein in a plant, and a method comprising the HA recombinant protein It relates to a pharmaceutical composition for preventing and treating influenza virus-infected diseases.
机译:本发明涉及一种用于设计衍生自甲型流感病毒表面蛋白的重组血凝素(HA)蛋白基因的方法,其形成三聚体,以及在植物中产生重组HA蛋白的方法。 具体而言,免疫原性增强和有效抗原设计一种能够以衍生自流感病毒表面蛋白的重组血凝素(HA)蛋白质的重组基因的方法,用于递送植物中HA重组蛋白的批量生产的方法 和包含HA重组蛋白的方法,其涉及用于预防和治疗流感病毒感染疾病的药物组合物。

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