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INTEGRATED NANOFLUIDIC DEVICES AND CIRCUITS

机译:集成的纳米设备和电路

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摘要

The fundamental length scales related to ions and molecules in liquids fall in the range of 1-100 nm. These involves the range of intermolecular forces due to steric interactions, electrostatic forces between charged species, and van der Waals interactions. This talk will focus on how confinement of aqueous solutions in the range of Debye screening length (1-50 nm) in nanochannels can lead to formation of unipolar ionic solutions. The ionic current in such nanochannels is found to several orders of magnitude higher than that predicted by macroscopic theories, and is extremely sensitive to surface charge, which can be used to study surface biomolecular reactions. Furthermore, this phenomenon can be exploited to develop nanofluidic transistors, diodes, and integrated circuits, which is now forming the basis for manipulating and analyzing complex mixtures of biomolecules in ultrasmall volumes.
机译:与液体中的离子和分子有关的基本长度尺度在1-100 nm的范围内。这些涉及由于空间相互作用,带电物质之间的静电力以及范德华相互作用而引起的分子间力的范围。本演讲将重点讨论在纳米通道中将水溶液限制在德拜屏蔽长度(1-50 nm)范围内如何导致单极性离子溶液的形成。发现这种纳米通道中的离子电流比宏观理论预测的离子电流高几个数量级,并且对表面电荷极为敏感,可用于研究表面生物分子反应。此外,可以利用这种现象来开发纳米流体晶体管,二极管和集成电路,这正成为处理和分析超小体积生物分子复杂混合物的基础。

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