Signals in mRNAs that Influence the Initiation of Translation

机译：mRNA中影响翻译起始的信号

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Signals in the mRNA influence how efficiently it is translated into protein. Previous studies have indicated that important signals are located around the initiation codon. In this study we describe a new approach to discovering these signals. This approach has been applied to 53 complete genomes or chromosomes. For the region flanking initiation codons most of the organisms fall into two groups containing previously known efficiency signals. However, we have identified several organisms with unusual signals that appear to utilise novel systems.

机译：mRNA中的信号影响将其翻译成蛋白质的效率。先前的研究表明，重要的信号位于起始密码子周围。在这项研究中，我们描述了一种发现这些信号的新方法。该方法已应用于53个完整的基因组或染色体。对于侧翼起始密码子区域，大多数生物体分为两组，其中包含先前已知的效率信号。但是，我们发现了几种具有异常信号的生物，这些生物似乎利用了新颖的系统。

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来源
《Asia-Pacific Bioinformatics Conference(APBC 2003); 200302; Adelaide(AU)》|2003年|P.203-206|共4页
会议地点 Adelaide(AU)
作者
Chris M Brown; Grant Jacobs; Mark Schreiber;
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作者单位

Biochemistry Department University of Otago PO Box 56, Dunedin, New Zealand;

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会议组织
原文格式 PDF
正文语种 eng
中图分类生物工程学（生物技术）;
关键词
information theory; translation; nucleotide bias;

机译：信息论;翻译;核苷酸偏向;

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1. Translation Initiation on mRNAs Bound by Nuclear Cap-binding Protein Complex CBP80/20 Requires Interaction between CBP80/20-dependent Translation Initiation Factor and Eukaryotic Translation Initiation Factor 3g [J] . Junho Choe, Nara Oh, Sungjin Park, The Journal of biological chemistry . 2012,第22期

机译：用核帽结合蛋白复合物CBP80 / 20结合MRNA的翻译引发需要CBP80 / 20依赖性翻译引发因子和真核翻译引发因子3G之间的相互作用
2. STRENGTH OF TRANSLATION INITIATION SIGNAL SEQUENCE OF MRNA AS STUDIED BY QUANTIFICATION METHOD - EFFECT OF NUCLEOTIDE SUBSTITUTIONS UPON TRANSLATION EFFICIENCY IN RAT PREPROINSULIN MRNA [J] . Lida Y, Masuda T Nucleic Acids Research . 1996,第17期

机译：定量方法研究的MRNA的转录起始信号序列的强度-核苷酸替代物对大鼠胰岛素原MRNA转化效率的影响。
3. Translation initiation with GUC codon in the archaeon Halobacterium salinarum: implications for translation of leaderless mRNA and strict correlation between translation initiation and presence of mRNA [J] . Srinivasan G, Krebs MP, RajBhandary UL Molecular Microbiology . 2006,第3期

机译：古细菌盐杆菌中GUC密码子的翻译起始：对无前导mRNA的翻译的意义以及翻译起始和mRNA存在之间的严格相关性
4. Signals in mRNAs that influence the initiation of translation [C] . Chris M. Brown, Grant Jacobs, Mark Schreiber Proceedings of the First Asia-Pacific bioinformatics conference on Bioinformatics 2003 . 2003

机译：mRNA中影响翻译起始的信号
5. Initiation of mRNA decay in Bacillus subtilis: Translational signals, 5' structure, and internal cleavage. [D] . Sharp, Josh. 2006

机译：枯草芽孢杆菌中mRNA降解的启动：翻译信号，5'结构和内部切割。
6. Translation Initiation on mRNAs Bound by Nuclear Cap-binding Protein Complex CBP80/20 Requires Interaction between CBP80/20-dependent Translation Initiation Factor and Eukaryotic Translation Initiation Factor 3g [O] . Junho Choe, Nara Oh, Sungjin Park, 2014

机译：核帽结合蛋白复合物CBP80 / 20结合的mRNA的翻译起始需要CBP80 / 20依赖性翻译起始因子和真核翻译起始因子3g之间的相互作用
7. Translation Initiation on mRNAs Bound by Nuclear Cap-binding Protein Complex CBP80/20 Requires Interaction between CBP80/20-dependent Translation Initiation Factor and Eukaryotic Translation Initiation Factor 3g [O] . Choe, J, Oh, N, Park, S, 2012

机译：核帽结合蛋白复合物CBP80 / 20结合的mRNA的翻译起始需要CBP80 / 20依赖性翻译起始因子和真核翻译起始因子3g之间的相互作用

Signals in mRNAs that Influence the Initiation of Translation

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