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首页> 外文会议>Conference on BioMEMS and Nanotechnology; 20071205-07; Canberra(AU) >DNA-conjugated metal nanoparticle for bioanalytics, nanophotonics and nanoelectronics
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DNA-conjugated metal nanoparticle for bioanalytics, nanophotonics and nanoelectronics

机译：DNA缀合的金属纳米颗粒，用于生物分析，纳米光子学和纳米电子学

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摘要

Metal (especially gold) nanoparticles exhibit unique electronic, optical, and catalytic properties. In order to utilize these properties, an integration of the particles into technical setups such as a chip surface is helpful. We develop techniques to use (bio) molecular tools in order to address and control the positioning of particles on microstructured chips. These techniques are utilized for novel DNA detection schemes using optical or electrical principles. Plasmonic properties of the particles and the combination of nano-apertures with particles are promising fields for further bioanalytical developments. On the other hand, methods for defined positioning of single molecules or molecular constructs in parallel approaches are under development, in order to provide needed defined nanostructures for applications in nanoelectronics. Connecting DNA with nanoparticles, metallization of DNA or positioning of individual DNA-structures over microstructured electrode gap including subsequent metal particle binding are important steps in this direction. The utilization of (bio) molecular tools and principles based on highly specific binding and self-assembly represent a promising development in order to realize novel nanoparticle-based devices for bioanalytics, nano-optics and -electronics.
机译：金属（尤其是金）纳米粒子具有独特的电子，光学和催化特性。为了利用这些特性，将颗粒集成到诸如芯片表面的技术设置中是有帮助的。我们开发使用（生物）分子工具的技术，以解决和控制微粒在微结构芯片上的定位。这些技术用于利用光学或电子原理的新型DNA检测方案。颗粒的等离子体性质以及纳米孔与颗粒的组合是进一步生物分析发展的有希望的领域。另一方面，正在开发用于以平行方式限定单个分子或分子构建体的定位的方法，以便提供用于纳米电子学中所需的限定的纳米结构。将DNA与纳米颗粒连接，DNA的金属化或单个DNA结构在微结构化电极间隙上的定位（包括随后的金属颗粒结合）是这个方向上的重要步骤。为了实现用于生物分析，纳米光学和电子学的新型基于纳米颗粒的装置，基于高度特异性结合和自组装的（生物）分子工具和原理的应用代表了一个有前途的发展。

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