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首页> 外文会议>Joint annual meeting of the International Society of Exposure Science and the International Society for Environmental Epidemiology >The Paraquat Exposures of Pregnant Women and Neonates in Agricultural Areas in Thailand
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The Paraquat Exposures of Pregnant Women and Neonates in Agricultural Areas in Thailand

机译：泰国农业地区孕妇和新生儿的百草枯暴露

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Although banned in over 50 countries, paraquat is a widely used herbicide in Thailand. Animal studies have found developmental impacts from fetal exposures, but there is no human data on potential fetal exposures among agricultural workers. This study recruited 79 pregnant women from three hospitals in agricultural areas in Thailand, and assessed paraquat concentrations in the urine of the women at 28 weeks of pregnancy, delivery and 2 months postpartum. Paraquat levels were also measured in the meconium of neonates. The subjects were interviewed about personal characteristics, agricultural activities and pesticide use patterns. The geometric mean (GSD) urinary paraquat concentrations at 28 weeks of pregnancy, delivery and 2 months postpartum were 2.04 (4.22), 2.06 (5.04) and 2.42 (5.33) ng/ml, respectively. The geometric mean (GSD) paraquat concentration in meconium was 33.31 (4.59) ng/g. There were no significant differences in urinary paraquat concentrations at 28 weeks of pregnancy, delivery and 2 months postpartum or in meconium levels between those whose self-reported occupation was agriculturist compared to those in non-agricultural occupations. However there were significant differences in paraquat exposures for those who reported agriculture related activities including: working outside, living near farmland where pesticides are sprayed, having a family member who is an agriculturist, drinking well water, or use of herbicides or use of paraquat by the pregnant woman or a family member.
机译：尽管百草枯已在50多个国家/地区禁止使用，但在泰国却被广泛使用。动物研究发现胎儿暴露会对发育产生影响，但尚无关于农业工人中潜在胎儿暴露的人类数据。这项研究从泰国农业地区的三家医院招募了79名孕妇，并评估了孕妇在怀孕28周，分娩时和产后2个月尿液中百草枯的浓度。还测量了新生儿胎粪中的百草枯含量。采访对象有关个人特征，农业活动和农药使用方式。妊娠，分娩和产后2个月时尿液百草枯的几何平均浓度（GSD）分别为2.04（4.22），2.06（5.04）和2.42（5.33）ng / ml。胎粪中百草枯的几何平均值（GSD）为33.31（4.59）ng / g。自我报告为农业职业者与非农业职业者相比，在妊娠，分娩，产后2周和产后2个月或胎粪中尿百草枯浓度无显着差异。但是，报告与农业有关的活动的人对百草枯的暴露量有显着差异，其中包括：在户外工作，在农药喷洒的农田附近生活，有一名农业专家家庭成员，饮用井水或使用除草剂或使用百草枯。孕妇或家庭成员。

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