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Simulation of trans-nasal endoscopy of the middle ear for visualization of cholesteatoma

机译：中耳经鼻内窥镜模拟胆脂瘤的可视化

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Cholesteatomas are benign lesions that form in the middle ear (ME). The standard of care is surgical removal. The traditional clinical approach for identifying cholesteatomas, visualization via a trans-aural approach, must be done in the operating room. This constraint complicates early diagnosis and treatment monitoring. Trans-nasal endoscopy of the ME may permit less invasive visualization as it could potentially be done in an outpatient setting. In this work, we propose a technique to quantitatively analyze the effectiveness of a trans-nasal endoscope for identifying cholesteatomas. Our approach is to quantify the surface area of MEs segmented in 6 CT volumes that is visible from a virtual endoscope inserted trans-nasally. Our preliminary results indicate that cholesteatomas located in certain sub-regions of the ME could indeed be well-visualized with a trans-nasal endoscope. Such an approach could have significant impact by facilitating earlier diagnosis and more frequent post-treatment monitoring of cholesteatomas.
机译：胆脂瘤是在中耳（ME）中形成的良性病变。护理标准是手术切除。识别胆脂瘤的传统临床方法，即通过经耳的方法进行可视化，必须在手术室中进行。这种限制使早期诊断和治疗监测变得复杂。经鼻鼻内镜检查可以允许侵入性较小的可视化，因为可以在门诊环境中进行。在这项工作中，我们提出了一种用于定量分析经鼻内窥镜识别胆脂瘤的有效性的技术。我们的方法是量化细分为6个CT体积的ME的表面积，该体积可从经鼻插入的虚拟内窥镜看到。我们的初步结果表明，经鼻内窥镜可以很好地可视化位于ME某些子区域的胆脂瘤。通过促进胆脂瘤的早期诊断和更频繁的治疗后监测，这种方法可能会产生重大影响。

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