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NOCTURNAL MELATONIN SUPPRESSION BY ADOLESCENTS AND ADULTS FOR DIFFERENT LEVELS, SPECTRA, AND DURATIONS OF LIGHT EXPOSURE

机译:夜间褪黑激素抑制青少年和成人不同级别,光谱和光曝光持续时间

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摘要

The 24-h pattern of light and dark on the retinas is the primary cue for entraining the human circadian system to the solar day, and nocturnal melatonin suppression is a primary marker of the biological clock's response to those light exposures. The development of circadian-effective lighting recommendations and light-treatment methods have been impeded by limited data relating to the combined effects of light level, spectrum, and exposure duration on nocturnal melatonin suppression. This study's primary goal was to measure nocturnal melatonin suppression for a wide range of light levels, 2 white light spectra, and extended exposure durations. The study also sought to provide an estimate of the absolute threshold for the impact of light on acute nocturnal melatonin suppression and to determine whether adolescents were more sensitive to short-wavelength light than middle-aged adults. Results showed significant main effects of light level, spectrum, and exposure duration on melatonin suppression.
机译:在视网膜上的光明和黑暗模式是将人昼夜系统纳入太阳日的主要提示,夜间褪黑激素抑制是生物钟对那些光曝光的响应的主要标记。昼夜有效的照明推荐和轻微治疗方法的发展已经受到与光水平,光谱和夜间褪黑素抑制术中的综合影响有关的有关数据的有限数据。本研究的主要目标是测量各种光水平,2个白光光谱和延长的曝光持续时间的夜间褪黑激素抑制。该研究还试图提供对光影响对急性夜间褪黑激素抑制的绝对阈值的估计,并确定青少年是否比中年成年人更敏感。结果表明光线水平,光谱和暴露持续时间对褪黑素抑制的显着影响。

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