It is established that fluoride can prevent or at least slow down the progression of carious lesions in enamel and, to a certain degree also dentine. According to presentday knowledge, small concentrations in saliva, plaque fluids or the aqueous phase of dental hard tissues are sufficient to achieve this goal, if the presence of fluoride is sustained for a prolonged period~1. This cannot be achieved with the classical topical administration e.g. toothpastes or mouthrinses. The reason thereof is the continuous secretion of saliva and its subsequent swallowing that shortens availability of fluoride in the oral cavity. Therefore several techniques and devices have been developed to ensure a longer-lasting release of fluoride into oral target areas. These techniques and devices can be subdivided into several groups: 1. varnishes; 2. restorative materials; 3 slow-release devices attached to: a) the dentition b) mucosal surfaces.
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