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Sound-induced activation of auditory cortices in patients with inner-ear hearing loss

机译:内耳听力损失患者的声音激活激活

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Studies on sound-induced activation of auditory cortices in patients with inner-ear hearing loss were reviewed. First, we recorded auditory evoked magnetic fields (AEFs) by presenting 1-kHz pure tone at four different intensities in normal subjects and in patients with inner-ear hearing loss. Increment of dipole moment of N100m was more rapid according to the stimulus intensity in patients compared with that in healthy subjects. Next, we measured AEFs by presenting white noise and speech-related sounds, AEF responses in patients were less dependent on the acoustic structure of the stimuli than in normal subjects. Although the N100m moments were larger in the right hemisphere in normal subjects, such interhemispheric differences were not identified in the patient group. In the third study, we made two word lists, well-perceived and poorly perceived words, and measured rCBF during their monaural presentation. Well-perceived words activated bilateral temporal lobes and left angular gyrus (AG), while poorly perceived words activated only the temporal lobe contralateral to the stimulated ear and little or no activation was observed in AG.
机译:综述了内耳听力损失患者声音皮质激活的研究。首先,我们通过在正常科目的四种不同强度下呈现1 kHz纯音,并在内耳听力损失的患者中录制听觉诱发磁场(AEF)。与健康受试者相比,根据患者的刺激强度,N100M的偶极矩的增量更快。接下来,我们通过呈现白噪声和语音相关的声音来测量AEF,患者的AEF反应依赖于刺激的声学结构而不是正常受试者。虽然正常受试者在右半球中N100M的瞬间在右半球中较大,但在患者组中没有鉴定这种卵闭差异。在第三次研究中,我们制作了两个单词列表,感知和感知良好的词语,并在单个展示期间测量了RCBF。感知的词语激活双侧颞叶和左角度(Ag),而在Ag中仅激活了颞叶对侧的颞叶对侧,并且在Ag中观察到很少或没有活化。

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