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Multi-modal evoked potentials in corticobasal degeneration, progressive supranuclear palsy and Alzheimer disease

机译:皮质缺血性退化,进步血清核麻痹和阿尔茨海默病的多模态诱发电位

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Short-latency somatosensory evoked potentials (SSEPs), auditory event-related potentials (ERPs), brainstera auditory evoked potentials (BAEPs) and visual evoked potentials (VEPs) were studied in 8 patients with corticobasal degeneration (CBD), 4 patients with progressive supranuclear palsy (PSP), 15 patients with Alzheimer disease (AD) and 15 normal control subjects. All patient groups showed significant prolongations of N200 and P300 latencies of ERPs compared with the normal controls. Patients with CBD showed significant prolongation of the interpeak latency between N13 andN20 (N13-N20) of SSEPs compared with the normal controls. In addition, CCT elicited by stimulation of the more affected side showed significant prolongation compared to CCT following stimulation of the less affected side. There were no significant differences in interpeak latencies between waves I and V of BAEP and P100 latency of VEPs among these four groups. The present results show that patients with CBD have different electrophysiological features, which may be usefiil for the differential diagnosis between CBD and PSP or AD.
机译:在8例皮质缺血性退化(CBD),4例患者中,研究了短期诱发的潜力(SSEPS),听觉事件相关潜力(ERP),Brainsta听觉潜力(ERP),Brainsta听觉诱发潜在(Baeps)和视觉诱发潜力(VEPS),4例患者进行了一次进步的血清核算麻痹(PSP),15例阿尔茨海默病(AD)和15名正常对照受试者。与正常对照相比,所有患者组都显示出ERP的N200和P300延迟的显着延长。与正常对照相比,患有CBD的患者表现出SSEPS的N13和N20(N13-N20)之间的闭嘴延迟的显着延长。此外,与刺激较小侧面刺激后的CCT相比,通过刺激刺激刺激的CCT显着延长。这四组中VEPS的Baep I和P100潜伏期之间的谵妄和v之间没有显着差异。本结果表明,CBD患者具有不同的电生理特征,可用于CBD和PSP或广告之间的差异诊断。

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