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首页> 外文会议>Conference on Biomedical Thermoacoustics, Optoacoustics, and Acousto-Optics >Technical considerations in quantitative blood oxygenation measurement using photoacoustic microscopy in vivo
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Technical considerations in quantitative blood oxygenation measurement using photoacoustic microscopy in vivo

机译：在体内光声显微镜测量的定量血氧测量技术考虑因素

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Using peak amplitude spectral PA measurements in the range of 570 - 600 nm, we found it possible to quantify blood oxygenation levels. Visible light illumination minimizes the inversion error of the PA measurements. Owing to high blood absorption in this optical regime, there is also an improved signal-to-noise ratio and less influence from optical scattering. To arrive at correct, and vessel size independent, SO2 measurements, the central frequency of the ultrasonic transducer must be high enough to satisfy the relation, that is above 25 MHz for a chosen optical wavelength region, although lower frequency transducers may produce correct results after correction of the optical absorption spectra. However, additional efforts are needed to achieve accurate SO2 values for in vivo measurements.
机译：在570-600nm的范围内使用峰值幅度谱PA测量，我们发现可以量化血氧水平。可见光照明最小化PA测量的反转误差。由于该光学方案中的高吸血，还存在改善的信噪比和光学散射的影响较小。要到达正确的，并且容器尺寸独立，SO2测量，超声换能器的中心频率必须足够高，以满足所选择的光波长区域的25 MHz的关系，尽管较低的频率传感器可能会产生正确的结果校正光学吸收光谱。然而，需要额外的努力来实现体内测量的准确SO2值。

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