首页> 外文会议>ASMS Conference on Mass Spectrometry and Allied Topics >Methods for Enhancing Sensitivity and Throughput in LC-MS Bioanalysis of BTEX Metabolites
【24h】

Methods for Enhancing Sensitivity and Throughput in LC-MS Bioanalysis of BTEX Metabolites

机译:增强BTEX代谢物LC-MS生物分析中敏感性和产量的方法

获取原文

摘要

Different compounds with different physicochemical characteristics have different trapping efficiencies. Using various flow rates of 0.25, 0.5, 1 and 2 mL/min did not have any significant effect on changing the experimental values of V_b of studied compounds on different studied trap columns. Using the low flow rate of 0.25 mL/min achieved the best trapping efficiency. MAYI trap C4 and C8 columns gave the highest values of efficiency and in most cases had very close values of efficiency. MAYI trap C18 had the lowest efficiency except for Dopamine HCl (highest hydrophilic) where it gave values close to that of C4 and C8 trap columns.
机译:具有不同物理化学特性的不同化合物具有不同的捕获效率。使用0.25,0.5,1和2mL / min的各种流速对改变不同研究的陷阱柱的V_B的实验值没有任何显着影响。使用0.25毫升/分钟的低流速实现了最佳的诱捕效率。 Mayi Trap C4和C8列给出了最高效率的值,并且在大多数情况下,具有非常接近的效率值。 Mayi Trap C18除了多巴胺HCl(热亲水性)之外的效率最低,其中它使值接近C4和C8捕集柱的值。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号