In Vitro Analysis of the Interaction Between Human Intestinal Epithelial Cells and Macrophage-Like Cells

机译：体外分析人肠上皮细胞和巨噬细胞样细胞之间的相互作用

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In addition to the function of absorbing nutrients, intestines have many defense mechanisms against exogenous substances such as bacteria and chemicals. Intestinal epithelial cells, which cover the surface of intestines function to keep intestinal homeostasis not only by acting as a barrier but also by interacting with immune cells located in the intestinal epithelium via soluble factors. But, in the intestines of the patients suffering from intestinal inflammation, hyperproduction of inflammatory cytokines, especially TNF-alpha, from immune cells such as activated macrophages, and damage of intestinal epithelial cells is observed. This is one of the causes of intestinal inflammation.

机译：除了吸收营养素的功能外，肠道还具有许多防止外源性物质的防御机制，如细菌和化学物质。肠上皮细胞，其覆盖肠道的表面功能，不仅通过作为屏障来保持肠道性稳态，而且还通过可溶性因子与位于肠上皮中的免疫细胞相互作用。但是，在患有肠炎症的患者的肠道中，观察到从免疫细胞如活化巨噬细胞的炎症细胞因子，特别是TNF-α的大实生产以及肠上皮细胞的损伤。这是肠道炎症的原因之一。

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《Annual and International Meeting of the Japanese Association for Animal Cell Technology》|2010年||共6页
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Yoko Ishimoto; Hideo Satsu; Tetsunosuke Moehizuki; Mamoru Totsuka; Makoto Shimizu;
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1. IEX-1 suppresses apoptotic damage in human intestinal epithelial Caco-2 cells induced by co-culturing with macrophage-like THP-1 cells [J] . Ishimoto Y., Satsu H., Totsuka M., Bioscience Reports . 2011,第5期

机译：IEX-1抑制与巨噬细胞样THP-1细胞共培养诱导的人肠上皮Caco-2细胞凋亡损伤
2. In vitro co-culture systems for studying molecular basis of cellular interaction between Aire-expressing medullary thymic epithelial cells and fresh thymocytes In vitro co-culture systems for studying molecular basis of cellular interaction between Aire-expressing medullary thymic epithelial cells and fresh thymocytes In vitro co-culture systems for studying molecular basis of cellular interaction between Aire-expressing medullary thymic epithelial cells and fresh thymocytes [J] . Nobuyoshi Shimizu, Tetsuhiko Yoshida, Yoshitaka Yamaguchi, Biology Open . 2014,第11期

机译：体外共培养系统研究表达Aire的髓样胸腺上皮细胞与新鲜胸腺细胞之间的细胞相互作用的分子基础体外共培养系统研究表达Aire的髓样胸腺上皮细胞与新鲜胸腺细胞之间的细胞相互作用的分子基础共培养系统，用于研究表达Aire的髓样胸腺上皮细胞与新鲜胸腺细胞之间的细胞相互作用的分子基础
3. The Sphingosine-1-Phosphate/Sphingosine-1-Phosphate Receptor 2 Axis in Intestinal Epithelial Cells Regulates Intestinal Barrier Function During Intestinal Epithelial Cells–CD4+T-Cell Interactions [J] . Chen T., Lin R., Jin S., Cellular Physiology and Biochemistry . 2018,第3期

机译：肠上皮细胞中的鞘氨醇-1-磷酸/鞘氨醇-1-磷酸受体2轴调节肠上皮细胞-CD4 + T细胞相互作用期间的肠屏障功能。
4. In Vitro Analysis of the Interaction Between Human Intestinal Epithelial Cells and Macrophage-Like Cells [C] . Yoko Ishimoto, Hideo Satsu, Tetsunosuke Moehizuki, Annual and International Meeting of the Japanese Association for Animal Cell Technology . 2010

机译：体外分析人肠上皮细胞和巨噬细胞样细胞之间的相互作用
5. Effects of Prebiotic fibre Diets on Rat Mucosal Intestinal and Systemic Immunity and in Vitro Mechanistic Analysis of Anti-Inflammatory Effects of Lactobacillus Strains on Rat and Human Intestinal Epithelial Cells. [D] . McCarville, Justin. 2012

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6. CD14 Is Expressed and Released as Soluble CD14 by Human Intestinal Epithelial Cells Cells In Vitro: Lipopolysaccharide Activation of Epithelial Cells Revisted [O] . David P. Funda, Ludmila Tučková, Maria A. Farré, 2001

机译：CD14被人类肠道上皮细胞体外表达和释放为可溶性CD14：脂多糖激活上皮细胞
7. CD14 Is Expressed and Released as Soluble CD14 by Human Intestinal Epithelial Cells In Vitro: Lipopolysaccharide Activation of Epithelial Cells Revisited [O] . Funda, David P., Tučková, Ludmila, Farré, Maria A., 2001

机译：CD14被人类肠道上皮细胞体外表达和释放为可溶性CD14：脂多糖激活上皮细胞

In Vitro Analysis of the Interaction Between Human Intestinal Epithelial Cells and Macrophage-Like Cells

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