首页> 外文会议>International Conference on Smart Materials Technologies >Biodegradation of Poly(3-Hydroxybutyrate) and Poly(3-Hydroxybutyrate-Co-3-Hydroxy-4-Methylvalerate) Films by Porcine Pancreatic Lipase
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Biodegradation of Poly(3-Hydroxybutyrate) and Poly(3-Hydroxybutyrate-Co-3-Hydroxy-4-Methylvalerate) Films by Porcine Pancreatic Lipase

机译:猪胰脂肪酶聚(3-羟基丁酸酯)和聚(3-羟基丁酸酯-CO-3-羟基-4-甲基甲基甲基甲基 - 甲基戊烯)膜的生物降解

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In the current work, the degradation of poly(3-hydroxybutyrate) (PHB) and poly(3-hydroxybutyrate-co-3-hydroxy-4-methylvalerate) (PHB4MV) films was studied in vitro by pancreatic lipase. The changes in film properties were traced by several analytical methods: the change of weight, molecular weight, and Young's modulus (by nanoindentation) were measured. During the six months of polymer films degradation the weight of samples decreased slightly, while a great increase in Young's modulus due to the relatively fast degradation of the amorphous areas was observed, as well as molecular weight of polymers decreased significantly. Weight loss of PHB4MV is faster than degradation rate of PHB, but the molecular weight of PHB 1700 decrease rapidly than PHB4MV; the Young's modulus of polymers remained relatively unchanged.
机译:在当前的工作中,通过胰腺脂肪酶在体外研究聚(3-羟基丁酸酯)(PHB)和聚(3-羟基丁酸酯-CO-3-羟基-4-甲基甲基甲基-4-羟甲基甲基甲基 - 4-甲基valergy)(PHB4MV)膜。通过几种分析方法跟踪膜性质的变化:测量重量,分子量和杨氏模量(通过纳米凸缘的变化。在聚合物薄膜的六个月内降解样品的重量略微下降,而观察到由于无定形区域的相对快速的劣化导致的杨氏模量的大大增加,以及聚合物的分子量显着降低。 PHB4MV的重量损失比PHB的降解速率快,但PHB 1700的分子量迅速减少而不是PHB4mV;年轻的聚合物模量保持相对不变。

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