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Effects Of (1→3), (1→6)-β-D-Glucan Behavior In Human Dermal Fibroblast Cells Under Serum Starvation

机译:(1→3),(1→6)-β-D-葡聚糖行为在血清饥饿下人体皮肤成纤维细胞中的影响

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Glucans have been reported to stimulate immunity and to promote wound healing. Adult human dermal fibroblast (aHDF) cultured in serum free (serum-starvation). Proliferation of aHDF was measured at various concentrations of β-glucan by MTT assay, and migration was observed for 36h on microscope. The result of fibroblast bioassay, β-glucan had positive influence. In this study, the direct effects of β-glucan on proliferation and migration of human dermal fibroblasts were examined in vitro. That means β-D-glucan has the effect to enhance proliferation and aHDF migration speed, and has the potential as a wound healing agent.
机译:据报道葡聚糖刺激了免疫力,促进伤口愈合。在无血清(血清饥饿)中培养的成人人类皮肤成纤维细胞(AHDF)。通过MTT测定以各种浓度的β-葡聚糖测量AHDF的增殖,在显微镜下观察到迁移36小时。成纤维细胞生物测定,β-葡聚糖具有阳性影响。在本研究中,在体外检查β-葡聚糖对人皮肤成纤维细胞的增殖和迁移的直接影响。这意味着β-D-葡聚糖具有增强增殖和AHDF迁移速度的效果,并且具有伤口愈合剂的潜力。

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