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首页> 外文会议>International Conference on Environmental, Industrial and Applied Microbiology >Probiotic strain Lactobacillus plantarum 1K reduces Salmonella enterica serovar Typhimurium infection in mice
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Probiotic strain Lactobacillus plantarum 1K reduces Salmonella enterica serovar Typhimurium infection in mice

机译：益生菌菌株Lactobacillus plantarum 1k减少了老鼠中的沙门氏菌肠道毒鼠伤寒

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摘要

The influence of the oral treatment with probiotic strain Lactobacillus plantarum 1K on an oral infection of mice by Salmonella enterica serovar Typhimurium was investigated. Mice were fed with milk-based diets supplemented with L. plantarum 1K for three days prior and following an oral challenge with S. Typhimurium. Survival, competition, adhesion and colonization of L. plantarum 1K and influence on infection with S. Typhimurium were monitored in the gastrointestinal tract. After the oral treatment of mice with L. plantarum 1K in combination with S. Typhimurium, the total number of lactic acid bacteria in faeces and in intestinal homogenates was increased, contrary, the total number of enterobacteria and Salmonella sp. was reduced. These results demonstrate that L. plantarum 1K can reduce the severity of infection due to the pathogenic S. Typhimurium, and suggest that this reduction is associated with competitive exclusion in the intestinal tract conferred by the L. plantarum 1K.
机译：研究了对益生菌菌株Lactobacillus Plantarum 1K对由沙门氏菌肠道毒蕈醋氏毒蕈的口腔感染对小鼠口腔感染的影响。小鼠用牛奶的饮食喂入补充有L.Purerarum 1K的牛蛙1K，并在与S. Typhimurium的口腔口腔挑战之后。 L.Purerarum 1K的存活，竞争，粘附和定植以及在胃肠道中监测胃肠道的影响。在用L.Purerarum 1K与S.鼠刺蘑菇组合的小鼠的口服处理后，粪便中乳酸菌和肠道匀浆的总数增加，相反，肠杆菌和沙门氏菌的总数。减少了。这些结果表明，L.Purerarum1k可以降低由于致病性S.培序血小痘引起的感染的严重程度，并表明该减少与L.Playarum 1K的肠道中的竞争排除相关。

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