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Fatal Incidence of Humidifier Disinfectants in Korea in 2011: Implications for Risk Management of Biocides of Inhalatory Concern

机译:2011年韩国加湿消毒剂的致命发病率:对吸入关注的生物剂风险管理的影响

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@@ The Korean Center for Disease Control and Prevention (KCDC) announced on August 31, 2011 that the 'unidentified fatal lung disease' found in Korea might have been caused by chemical disinfectants used with household humidifiers. The impact of the chemical incidence was appalling to the society due to its human fatality by abrupt discovery of the symptom and almost rare recovery by medical treatment. Based on the epidemiological investigation that active ingredients of disinfecting products caused this disease, a subchronic 90-day rat inhalation toxicity testing was conducted with 3 commercial disinfecting products which had been found to be the most commonly consumed ones by the patients and families. By November of 2011, the KCDC and concerned experts concluded that the histopathological readings of human patients, bronchiolar fibrosis, and the ones of rats which inhaled products with polyalkylguanidine moiety are identical and The KCDC ordered recalling all the products containing guanidine moiety.
机译:@@韩国疾病控制和预防中心(KCDC)于2011年8月31日宣布,韩国发现的“未识别的致命肺病”可能是由家用加湿器使用的化学消毒剂引起的。通过突然发现症状和医疗几乎罕见的恢复,将化学发病率的影响令人震惊。基于流行病学调查,消毒产品的活性成分引起这种疾病,次级调整为90天大鼠吸入毒性测试,用3种商业消毒产品进行,发现是患者和家庭最常用的产物。到2011年11月,KCDC和有关专家得出结论,人类患者,支气管纤维化纤维化和吸入聚烷基胍部分的大鼠的组织病理学读数是相同的,并且KCDC命令召回含有胍基部分的所有产品。

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