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首页> 外文会议>International Conference on Biomedical and Biological Engineering >Anticancer Activity of Oridonin Against Esophageal Cancer Cells Enhanced by Special Electromagnetic Field Treated Water
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Anticancer Activity of Oridonin Against Esophageal Cancer Cells Enhanced by Special Electromagnetic Field Treated Water

机译：通过特殊电磁场处理的水增强了对食管癌细胞的抗癌活性

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Oridonin, the main pharmacological active substance isolated from Rabdosia Rubescens, has been found to show anti-inflammatory, pro-apoptotic, neurological effects, and excellent anticancer activities. However, the clinical application of oridonin is still limited by its poor solubility. The special electromagnetic field treated water (SEFT water) is served as a kind of high quality drinking water in China. In the present work, the SEFT water was used to test its effects on the anticancer activity of oridonin. And we found that the proliferation inhibition effects of oridonin in EC9706 cells were enhanced in SEFT water dissolved DMEM medium. And the apoptosis induction effects of oridonin in EC9706 cells were also enhanced in SEFT water dissolved DMEM medium, implying that SEFT water could enhance the anticancer effects of oridonin in cancer cells. It was also worth to note that the solubility of oridonin was also enhanced in SEFT water, which might contribute to the enhanced anticancer effects of oridonin in SEFT water dissolved medium for cancer cells.
机译：冬凌草甲素，冬凌草分离出的主要药理活性物质，已被发现显示出抗炎，促凋亡，神经系统的影响，以及优良的抗癌活性。然而，冬凌草甲素的临床应用仍然受到其溶解性差的限制。特殊的电磁场处理过的水（SEFT水）担任中国的一种高品质的饮用水。在目前的工作中，SEFT水被用来测试对冬凌草甲素的抗癌活性其影响。而且我们发现，在EC9706细胞冬凌草甲素增殖抑制效果在SEFT水溶解DMEM培养基中增强。和在EC9706细胞冬凌草甲素诱导凋亡的作用也得到了加强在SEFT水中溶解的DMEM培养基中，这意味着SEFT水可提高冬凌草甲素在癌细胞中的抗癌作用。还值得注意的是冬凌草甲素的溶解度也得到增强在SEFT水，这可能有助于在SEFT水溶解介质冬凌草甲素增强抗癌作用为癌细胞。

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