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Genetic Etiology of Tumors with Genome-Wide Association Study

机译：基因组关联研究肿瘤的遗传病程

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Cancer is a complex disease caused by gene-environment interaction. In the same environmental exposure, the risk of individuals with different genetic backgrounds of cancer is very different. The related factors of tumor genetic research have important significance in understanding the genesis and development of tumor diagnosis and treatment. A genome-wide association study in recent years, the development of genome-wide (association study, GWAS) can be found that genetic factors associated with complex disease or phenotype in whole genome range, provides a powerful means for the study of complex disease genetics. Researchers in the United States and Europe using genome-wide closed method research, on a variety of common cancers studied, has obtained important results in. 2010, China scientists published a series of high the level of tumor genome-wide association study results in international core journals, the Chinese common tumor in genetic disease Significant progress has been made in the field of scientific research.
机译：癌症是由基因环境相互作用引起的复杂疾病。在相同的环境暴露中，癌症不同遗传背景的个体的风险非常不同。肿瘤遗传研究的相关因素对了解肿瘤诊断和治疗的成因和发展具有重要意义。近年来的基因组协会研究，可以发现基因组（关联研究，GWAs）的发展，即全基因组范围内与复杂疾病或表型相关的遗传因素为复杂疾病遗传学提供了一种强大的方法。美国和欧洲的研究人员使用基因组封闭方法研究，在各种常见的癌症中研究，已经获得了重要成果。2010年，中国科学家刊登了一系列高度肿瘤基因组关联研究结果在国际上核心期刊，中国常见肿瘤在遗传疾病中取得了重大进展，在科研领域取得了重大进展。

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