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首页> 外文会议>SPIE Conference on Colloidal Nanoparticles for Biomedical Applications >Effects of iron-oxide nanoparticles on compound biofilms of Streptococcus gordonii and Fusobacterium nucleatum
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Effects of iron-oxide nanoparticles on compound biofilms of Streptococcus gordonii and Fusobacterium nucleatum

机译：铁 - 氧化铁纳米粒子对链球菌和Fusobacterium核心核化合物生物膜的影响

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摘要

The human mouth is a host of a large gamut of bacteria species, with over 700 of different bacteria strains identified. Most of these bacterial species are harmless, some are beneficial (such as probiotics assisting in food digestion), but some are responsible for various diseases, primarily tooth decay and gum diseases found in gingivitis and periodontitis. Dental plaque comprises a complicated biofilm structure that varies from patient to patient, but a common factor in most cases is the single species of bacterium acting as a secondary colonizer, namely Fusobacterium nucleatum, while the actual disease is caused by a variety of tertiary colonizers. We hypothesize that the destruction of a compound biofilm containing F. nucleatum will prevent tertiary colonizers from establishing a harmful biofilm, and thus will protect the patient from developing gingivitis and, consequently, periodontitis. In this paper, we report on the effects of exposure of compound biofilms of a primary colonizer Streptococcus gordonii combined with F. nucleatum on a hydroxyapatite substrate to iron oxide nanoparticles as possible bactericidal agent.
机译：人的嘴是一个大色域的细菌种类的主机，以不同的细菌超过700株鉴定。大多数这些细菌种类是无害的，有些是有益的（如益生菌食物的消化援助），但有些是负责各种疾病，主要是龋齿和牙龈疾病，牙龈炎发现和牙周炎。牙菌斑包括从患者变化到患者体内的复杂的生物膜结构，但在大多数情况下的一个共同因素是充当次级殖民者，即具核梭杆菌细菌的单一物种，而实际的疾病是由多种叔胺殖民者引起的。我们假设，含有具核的化合物的生物膜的破坏将防止建立有害生物膜叔殖民者，并且因此将保护患者免于发展牙龈炎，因此，牙周炎。在本文中，我们在主殖民者氏链球菌与具核羟基磷灰石基质以氧化铁纳米颗粒尽可能杀菌剂上结合的化合物生物膜的照射的影响的报告。

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