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Working Postures and 22-Year Incidence of Acute Myocardial Infarction

机译：急性心肌梗死的工作姿势和22年发生率

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Introduction: In contrast to body postures during the entire day or during leisure, associations of work postures with acute myocardial infarction (AMI) have not been examined while adjusting for socioeconomic status, leisure time physical activity, fitness, and other CVD risk factors. Methods: The associations between work postures (assessed by questionnaire at baseline) and 22-year incidence of first AMI (ascertained via record linkage with national registries) were estimated by Cox regression models adjusting for 19 confounders among 1831 Finnish men, separately for those with (n= 1515) and without (n= 316) pre-existing ischemic heart disease (IHD). Results: In the full sample, work postures showed no substantial associations with AMI risk except for "standing quite a lot" (HR 1.26; 95%CI 0.94-1.70). The effects of work postures differed by baseline IHD status. Among men without IHD, sitting showed 7-16% reduced risks, standing 4-21% increased risks, and walking had no impact. Among men with IHD, walking showed 18-23% reduced risks, sitting "quite a lot" or "very much" showed 28% and 67% increased risks, respectively. Standing "a little" (HR 1.38, 95%CI 0.79-2.42) and "quite a lot" (HR 1.33, 95%CI 0.73-2.41) were positively but standing "very much" (HR 0.68, 95%CI 0.36-1.32) inversely associated with AMI. Conclusions: Considering previously reported strong positive associations between standing and progression of atherosclerosis the latter finding is probably due to healthy worker selection bias. It is therefore prudent not to recommend standing at work for men with IHD and to always consider IHD status when assessing risks and benefits of different work postures.
机译：简介：与整天或休闲期间的身体姿势相比，工作姿势与急性心肌梗死（AMI）的关联尚未在调整社会经济地位，休闲时间体育活动，健身和其他CVD危险因素的同时进行检查。方法：工作姿势（按基线问卷评估）的协会和第一个AMI的22年发病率（通过记录联系与国家登记处）估计，在1831名芬兰男子之间调整19个混淆，分别为那些（n = 1515），没有（n = 316）预先存在的缺血性心脏病（IHD）。结果：在完整的样本中，除了“站立得很大”（HR 1.26; 95％CI 0.94-1.70）之外，工作姿势没有与AMI风险的大量关联。工作姿势的影响因基线IHD状态而不同。在没有IHD的男性中，坐姿减少了7-16％，风险增加4-21％，行走没有影响。在IHD的男性中，散步表现出18-23％的风险，坐在“相当多”或“非常”的情况下，分别增加了28％和67％的风险。站在 “三多一少”（HR 1.38，95％CI 0.79-2.42）和 “相当多”（HR 1.33，95％CI 0.73-2.41）为正但站在 “非常多”（HR 0.68，95％CI 0.36- 1.32）与AMI反向相关。结论：考虑到先前报告了动脉粥样硬化的站立和进展之间的强大积极协会，后者发现可能是由于健康的工人选择偏见。因此，不建议在评估不同工作姿势的风险和福利时始终考虑IHD状态的男性工作。

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