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首页> 外文会议>American College of Veterinary Internal Medicine Forum Conference >Analgesic Effects of Gabapentin Alone or in Combination with Meloxicam in Dogs with Neuropathic Pain
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Analgesic Effects of Gabapentin Alone or in Combination with Meloxicam in Dogs with Neuropathic Pain

机译：加布普坦单独的镇痛作用，或与犬犬在狗中与神经病疼痛组合的影响

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This study aimed to evaluate the analgesic effects of gabapentin alone (G) or in combination with meloxicam (GM) in dogs with naturally occurring neuropatiiic pain. Twenty-nine client-owned painful dogs were included in a prospective, randomized, clinical trial after physical and neurological examination, and lesion confirmation via MRI. Dogs were allocated to receive G/placebo/GM or GM/placebo/G during 21 days (7 days/treatment including resting). Client specific-outcome measures (CSOM) and Canine Brief Pain Inventory (CBPI; pain, function and overall impression), and dynamic and interactive visual analog scale (DIVAS; mm) and Glasgow pain scale-short form (CMPS-SF) were evaluated by owners (blinded to treatments) or a single veterinary neurologist (blinded to treatment order), respectively, at presentation and at days 7,14 and 21. Statistical analysis included mixed linear models and Cochran-Mantel-Haenszel followed by adjustment of alpha level when appropriate (p<0.05).
机译：本研究旨在评估种植蛋白（G）或与美洛昔康（GM）组合的狗在狗中进行自然存在的神经疼痛。在物理和神经学检查后的前瞻性，随机的，临床试验中包含二十九所痛苦的狗，并通过MRI病变确认。在21天内分配狗以接受G /安慰剂/ gm或GM /安慰剂/ g（包括休息的7天/治疗）。客户特定结果措施（CSOM）和犬短暂疼痛库存（CBPI;疼痛，功能和整体印象），以及动态和交互式视觉模拟量表（DIVAS; MM）和Glasgow疼痛秤 - 短型（CMPS-SF）进行了评估由业主（盲目的治疗）或单个兽医分别在介绍和7,14和21天（盲目的治疗顺序）。统计分析包括混合线性模型和Cochran-Mantel-Haenszel，然后调整α水平适当时（P <0.05）。

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