首页> 外文会议>International Conference on Inter-professional Health Collaboration >The Analysis Of Rbmyl Sts Rbmi Microdeletion Gene On Azoospermic Factor (Azf) Region Of The Y Chromosome In Infertile Men In Palembang
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The Analysis Of Rbmyl Sts Rbmi Microdeletion Gene On Azoospermic Factor (Azf) Region Of The Y Chromosome In Infertile Men In Palembang

机译:柏陵宫不含染色体染色体(AZF)区rbmyl sts RBMI微蛋白酶蛋白(AZF)区的分析

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Approximately 50-80 million couples have infertility problems, and every year appeared about 2 million new infertile couples. As many as 40% of them are caused by male factors. Male infertility generally occursdue to abnormal spermatozoa. One of the causes is related to the deletion of gene on Azoospermic Factor (AZF) regionof the Y chromosome. One of the candidate genes in that region is RBMY1. This study is a descriptive study that aims to determine the molecular frequency RBMY1 gene microdeletion in AZF region of the Y chromosome uses STS RBMI in infertile men in Palembang. The number of samples was 39 people. The analysis was done by using Polymerase Chain Reaction (PCR) and electrophoresis on 2% agarose gel. From this research, it was found that the frequency of microdeletions on the AZF region of the Y chromosome uses STS RBM1 of infertile men in Palembang was 7.7%. Further studies on microdeletion region of Azoospermic factor (AZF) of the Y chromosome in interfile menin Palembang, with other genes or by using criteria on only male factor, for example oligozoospermia, oligozoospermia extreme or cryptozoospermia were used as samples.
机译:大约50-80百万夫妇有不孕症问题,每年都出现了大约200万新的不孕夫妇。它们的40%是由男性因素引起的。男性不孕症通常静止异常的精子。其中一种原因与Y染色体缺血因子(AZF)区域删除基因。该地区的候选基因之一是RBMY1。该研究是一种描述性研究,旨在确定Y染色体AZF区域的分子频率RBMY1基因微缺细胞使用STS RBMI在Palembang中的不育。样品数量为39人。通过在2%琼脂糖凝胶上使用聚合酶链反应(PCR)和电泳来完成分析。从这项研究开始,发现Y染色体AZF区域的微缺失频率使用Palembang中不育男性的STS RBM1为7.7%。进一步研究杂交患者杂交系数(AZF)的杂蛋白酶体(AZF),与其他基因或仅在仅使用雄性因子,例如寡核糖菌,寡核糖药物,寡核糖药物,寡核苷酸症,以样品为样品。

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