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Effects of Curcumin and Pentagamavunon-0 Against Dengue-2 Virus Infection In Vero Cells;; an In Vitro Study

机译:姜黄素和五百伐单抗-0对VERO细胞登革热-2病毒感染的影响;体外研究

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The research aims was to determine the cytotoxic effects and the highest safe concentration of curcumin and PGV-0 on vero cells. This research also compare the effect of curcumin and PGV-0 against vero cells infected by Dengue virus (in vitro) in one and three days incubation period. The highest safe concentrations against vero cells from curcumin was 6.25 ppm and 1.5625 ppm for PGV-0. Immunocytochemistry test of curcumin and PGV-0 in both incubation period (one and three days) shows no significant difference (significant value 0.925), but RT-PCR result indicates that PGV-0 have potential antiviral better than curcumin.
机译:该研究旨在确定在VERO细胞上的细胞毒性效应和最高安全浓度的姜黄素和PGV-0。该研究还将姜黄素和PGV-0对孵化期(体外)感染的Vero细胞的影响进行比较。对来自姜黄素的Vero细胞的最高安全浓度为6.25ppm和1.5625ppm的pGV-0。姜黄素和PGV-0的免疫细胞化学测试在孵化期(一和三天)中显示出没有显着差异(显着的值0.925),但RT-PCR结果表明PGV-0比姜黄素更好地抗病毒。

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