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Imaging of highly scattering media by spatially modulated pulsed light

机译:通过空间调制脉冲光对高散射介质成像

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摘要

The use of spatially modulated light is finding application in biomedical optics having potential use in imaging and tomography of tissues and small animals. We describe the time-resolved propagation of spatial frequencies in turbid media. We present a set-up based on a ps laser source, spatially modulated by a micro-mirror device and a time-gated intensifier. We discuss the relevant information content that can be useful for imaging of tissues, in terms of the spatial Fourier components of the propagating pulse. We demonstrate that high spatial frequencies appear in the early time-gated signal whereas low frequencies persist for longer times and that the combined use of high spatial frequencies and early time gates can be used to improve the resolution in imaging.
机译:空间调制光的使用正在生物医学光学中找到应用,其在组织和小型动物的成像和层析成像中具有潜在的用途。我们描述了在混浊介质中空间频率的时间分辨传播。我们提出了一种基于ps激光源的设置,该设置由微镜设备和时间门控放大器进行空间调制。我们根据传播脉冲的空间傅立叶分量,讨论了可用于组织成像的相关信息内容。我们证明了高空间频率出现在早期的时间门控信号中,而低频持续了较长的时间,并且高空间频率和早期时间门的组合使用可以用来提高成像的分辨率。

著录项

  • 来源
  • 会议地点 San Jose CA(US)
  • 作者单位

    IIT, ULTRAS-CNR-INFM and IFN-CNR Dept. of Physics, Politecnico di Milano, Piazza Leonardo da Vinci 32, Milano, 20133, Italy;

    IIT, ULTRAS-CNR-INFM and IFN-CNR Dept. of Physics, Politecnico di Milano, Piazza Leonardo da Vinci 32, Milano, 20133, Italy;

    IIT, ULTRAS-CNR-INFM and IFN-CNR Dept. of Physics, Politecnico di Milano, Piazza Leonardo da Vinci 32, Milano, 20133, Italy;

    IIT, ULTRAS-CNR-INFM and IFN-CNR Dept. of Physics, Politecnico di Milano, Piazza Leonardo da Vinci 32, Milano, 20133, Italy;

    Centre for Medical Image Computing, University College London, Malet Place, London WC1E 6BT, United Kingdom;

  • 会议组织
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    modulated imaging; turbid medium; time-resolved;

    机译:调制成像浑浊的介质;时间解决;

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