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首页> 外文会议>Optical tomography and spectroscopy of tissue XII >A novel approach for the time-domain fluorescence imaging of a semi-infinite turbid medium: Monte Carlo evaluation
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A novel approach for the time-domain fluorescence imaging of a semi-infinite turbid medium: Monte Carlo evaluation

机译：半无限浑浊介质的时域荧光成像的新方法：蒙特卡洛评估

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摘要

We investigated the feasibility of a two-step scheme for reconstruction of a fluorophore target embedded in a semi-infinite medium. In this scheme, we neglected the presence of the fluorophore target for the excitation light and used an analytical solution of the time-dependent radiative transfer equation (RTE) for the excitation light in a homogeneous semi-infinite media instead of solving the RTE numerically in the forward calculation. In the first step of this reconstruction scheme, we implemented a pixel-based reconstruction using the Landweber method with adjoint fields. The second step uses this result as an initial guess for solving the shape and contrast value reconstruction problem using the level set method. Numerical experiments using Monte Carlo data measurements, show that the proposed scheme provides reconstructions of shape, location and contrast value of the target with rather good accuracy. The computation times of the solution of the forward problem and the whole reconstruction process were reduced by about forty and fifteen percent, respectively.
机译：我们研究了两步法重建嵌入半无限介质中的荧光团靶标的可行性。在该方案中，我们忽略了激发光的荧光团靶标的存在，而是在均匀的半无限介质中对激发光使用了时变辐射传递方程（RTE）的解析解，而不是用数值方法求解RTE。向前计算。在此重建方案的第一步中，我们使用具有伴随场的Landweber方法实施了基于像素的重建。第二步将此结果用作使用级别设置方法解决形状和对比度值重建问题的初步猜测。使用蒙特卡洛数据测量的数值实验表明，所提出的方案以相当好的精度提供了目标的形状，位置和对比度值的重建。正问题求解的计算时间和整个重构过程分别减少了约百分之四十五和百分之十五。

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