• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文会议>Photons Plus Ultrasound: Imaging and Sensing 2006; Progress in Biomedical Optics and Imaging; vol.7, no.9 >The combination of pulsed acousto-optic imaging and B-mode diagnostic ultrasound for three-dimensional imaging in ex vivo biological tissue
【24h】

The combination of pulsed acousto-optic imaging and B-mode diagnostic ultrasound for three-dimensional imaging in ex vivo biological tissue

机译：脉冲声光成像与B型诊断超声的结合，用于离体生物组织的三维成像

获取原文
获取原文并翻译 | 示例
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

A multimode imaging system, producing conventional ultrasound (US) and acousto-optic (AO) images, has been developed and used to detect optical absorbers buried in excised biological tissue. A commercially-available diagnostic ultrasound imaging transducer is used to both generate B-mode ultrasound images and as a pump for AO imaging. Due to the fact that the steered and focused beam used for US imaging and the US source for pumping the AO image are generated from the same ultrasound probe, the acoustical and optical images are intrinsically co-registered. AO imaging is performed using short ultrasound pulse trains at a frequency of 5 MHz. The phase-modulated light emitted from the interaction region is detected using a photorefractive-crystal based interferometry system. Experimental results have previously been presented for the two-dimensional imaging in tissue-mimicking phantoms. In this paper, we report further experimental developments demonstrating three-dimensional fusion of B-mode ultrasound imaging and pulsed acousto-optic imaging in excised biological tissue (～2 cm thick). By mechanically scanning the ultrasound transducer array in a direction perpendicular to its imaging plane, both the acoustical and optical properties of an embedded target are obtained in three dimensions. The results suggest that AO imaging could be used to supplement conventional B-mode ultrasound imaging with optical contrast, and the multimode imaging system may find application in the detection and diagnosis of cancer.
机译：已经开发了产生常规超声（US）和声光（AO）图像的多模成像系统，并将其用于检测掩埋在切除的生物组织中的光学吸收体。商业上可获得的诊断超声成像换能器既用于生成B模式超声图像，又用作AO成像的泵。由于用于US成像的转向光束和聚焦光束以及用于泵送AO图像的US光源是从同一超声探头生成的，因此声学和光学图像在本质上是共配准的。使用短超声脉冲序列以5 MHz的频率执行AO成像。使用基于光折射晶体的干涉仪系统检测从相互作用区域发出的调相光。先前已经针对组织模拟体模中的二维成像提出了实验结果。在本文中，我们报告了进一步的实验进展，这些实验表明了B型超声成像和脉冲声光成像在已切除的生物组织（约2厘米厚）中的三维融合。通过在垂直于其成像平面的方向上机械扫描超声换能器阵列，可以在三个维度上获得嵌入目标的声学和光学特性。结果表明，AO成像可用于补充常规B型超声成像的光学对比度，并且多模成像系统可在癌症的检测和诊断中找到应用。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号