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首页> 外文会议>Plasma for bio-decontamination, medicine and food security >Medical Plasma in Dentistry: A Future Therapy for Peri-implantitis
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Medical Plasma in Dentistry: A Future Therapy for Peri-implantitis

机译：牙科医学血浆：种植体周围炎的未来治疗

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摘要

Biofilm formation plays a major role in the pathogenesis of many oral diseases especially in peri-implantits. To evaluate the anti-biofilm effect of different plasma devices and processes we used different dental biofilm models: Candida albicans, Streptococcus mutatis, Streptococcus sanguinis, aerobe multispecies human saliva and anaerobe plaque biofilms. After 10 min treatment we reduced the biofilms by 5 log_(10) steps using dielectric barrier discharge (DBD) plasma. Chlorhexidine is the gold standard antiseptic which achieved in the same time only a 1.5 log_(10) reduction. All plasma devices (DBD or plasma jets) damaged the membrane of the microorganisms but only etching plasma sources can remove the biofilm as shown in CLSM micrographs. It is possible to improve the plasma process using antiseptics like octenidine. This combination significantly reduced CFU values after 1 min plasma treatment compared to the plasma control. Beside the anti-biofilm effect an additional effect of plasma is the contact angle reduction of different titanium implant surfaces from 90° to super-hydrophilic (<5°). This can improve the implant healing process. Thus in the future, plasma could be an interesting treatment option in dentistry, especially in treatment of peri-implantits.
机译：生物膜的形成在许多口腔疾病的发病机理中起着重要作用，尤其是在种植体周围。为了评估不同血浆装置和工艺的抗生物膜作用，我们使用了不同的牙科生物膜模型：白色念珠菌，比照链球菌，血红链球菌，多菌种人唾液和厌氧菌斑生物膜。处理10分钟后，我们使用介电势垒放电（DBD）等离子体将生物膜减少了5 log_（10）个步骤。洗必太是金标准的防腐剂，仅在同一时间就可降低1.5 log_（10）。所有血浆设备（DBD或血浆喷射器）都会破坏微生物的膜，但是只有蚀刻血浆源才能去除生物膜，如CLSM显微照片所示。使用防腐剂（例如奥替尼定）可以改善血浆过程。与血浆对照相比，这种组合在血浆处理1分钟后显着降低了CFU值。除抗生物膜作用外，等离子体的另一作用是将不同钛植入物表面的接触角从90°减小到超亲水性（<5°）。这可以改善植入物的愈合过程。因此，在将来，血浆可能是牙科中一种有趣的治疗选择，尤其是在种植体周围的治疗中。

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  • 来源
  • 会议地点 Demanovska Dolina(SK)
  • 作者

    Ina Koban; Lukasz Jablonowski; Axel Kramer; Klaus-Dieter Weltmann; Thomas Kocher;

  • 作者单位

    Unit of Periodontology, Policlinics for Restorative Dentistry, Periodontology and Endodontology, Ernst-Moritz-Anrdt University, Walther-Rathenau-Str. 49a, 17489 Greifswald, Germany;

    Unit of Periodontology, Dental School, Ernst-Moritz-Arndt University Greifswald, Rotgerber Str. 8, 17475 Greifswald, Germany;

    Institute for Hygiene and Environmental Medicine, Ernst-Moritz-Arndt University Greifswald, Walther-Rathenau-Strasse 49a, 17489 Greifswald, Germany;

    Leibniz Institute for Plasma Science and Technology e. V. (INP Greifswald), Felix-Hausdorff-Str.2, Walther-Rathenau-Strasse 49a, 17489 Greifswald, Germany;

    Unit of Periodontology, Dental School, Ernst-Moritz-Arndt University Greifswald, Rotgerber Str. 8, 17475 Greifswald, Germany;

  • 会议组织
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 生物工程学（生物技术）;
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