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Novel Stochastic Framework for Accurate Segmentation of Prostate in Dynamic Contrast Enhanced MRI

机译:用于动态对比增强MRI的前列腺精确分割的新型随机框架

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Prostate segmentation is an essential step in developing any non-invasive Computer-Assisted Diagnostic (CAD) system for the eaxly diagnosis of prostate cancer using Dynamic Contrast Enhancement Magnetic Resonance Images (DCE-MRI). In this paper we propose a novel approach for segmenting the prostate region from DCE-MRI based on using a graph cut framework to optimize a new energy function consists of three descriptors: (i) 1st-order visual appearance descriptors of the DCE-MRI; (ii) a spatially invariant 2nd-order homogeneity descriptor, and (iii) a prostate shape descriptor. The shape prior is learned from a subset of co-aligned training images. The visual appearances are described with marginal gray level distributions obtained by separat ing their mixture over the image. The spatial interactions between the prostate pixels are modeled by a 2nd-order translation and rotation invariant Markov-Gibbs random field of object / background labels with analytically estimated potentials. Experiments with prostate DCE-MR images confirm robustness and accuracy of the proposed approach.
机译:前列腺分割术是开发使用动态对比增强磁共振图像(DCE-MRI)进行前列腺癌的早期诊断的任何非侵入性计算机辅助诊断(CAD)系统的重要步骤。在本文中,我们提出了一种新的方法,该方法基于图切割框架来优化新的能量函数,从而从DCE-MRI分割前列腺区域,该方法包括三个描述符:(i)DCE-MRI的一阶视觉外观描述符; (ii)空间不变的2阶均匀性描述子,以及(iii)前列腺形状描述子。从共同对准的训练图像的子集中学习形状先验。通过将边缘混合在图像上分离获得的边缘灰度分布来描述视觉外观。前列腺像素之间的空间相互作用通过对象/背景标签的具有分析估计电位的二阶平移和旋转不变马尔可夫-吉布斯随机场进行建模。前列腺DCE-MR图像的实验证实了该方法的鲁棒性和准确性。

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