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The Influence of HIV Stigma on Adherence to Antiretroviral Therapy in HIV Positive Gay Men Age 50 and Older

机译:在50岁及以上的HIV阳性男同性恋者中,HIV耻辱对坚持抗逆转录病毒疗法的影响

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摘要

This secondary data analysis examined the influence of HIV stigma on antiretroviral therapy (ART) adherence in 180 HIV infected gay men age 50 and older. Adherence to ART is necessary to maintain individual health and to prevent the spread of the virus to others. The effects of HIV stigma contribute to suboptimal adherence, which leads to negative health outcomes and greater infectiousness. As a direct result of ART, those infected with the virus are living into old age. Gay men over 50 comprise the largest single group with HIV/AIDS in this country and, consequently, have the highest potential for forward viral transmission. There have been few studies of the influence of HIV stigma on ART adherence, and almost no research in this area devoted to older gay men. In addition to a direct effect, this study hypothesized that depression and substance use would act as mediators. Confirmatory factor analysis revealed that depression, but not substance use, partially mediated the relationship between HIV stigma and ART adherence. While not a mediator, substance use was significantly related to adherence. Overall, this study supported a significant relationship between HIV stigma and adherence to ART. The findings bring into focus the need to include HIV stigma in the design of interventions intended to reduce stigma. The direct relationship between HIV stigma and ART adherence supported in this study suggests the need for research into other distal psychosocial factors that may influence adherence to ART.
机译:这项二级数据分析检查了180名年龄在50岁及以上的HIV感染男同性恋者中艾滋病毒柱头对抗逆转录病毒疗法(ART)依从性的影响。坚持抗逆转录病毒疗法对维持个人健康和防止病毒向他人传播至关重要。 HIV污名的影响导致依从性不佳,导致不良的健康结果和更大的传染性。作为抗逆转录病毒治疗的直接结果,那些感染了这种病毒的人正在老龄化。在这个国家,年龄超过50岁的同性恋者是艾滋病毒/艾滋病中最大的一个群体,因此,向前传播病毒的潜力最大。很少有关于艾滋病毒耻辱对抗逆转录病毒依从性的影响的研究,并且在这一领域几乎没有专门针对老年同性恋者的研究。除了直接的影响外,该研究还假设抑郁症和药物滥用会起到调节作用。验证性因素分析显示,抑郁而非药物滥用部分地介导了艾滋病毒柱头与抗逆转录病毒依从性之间的关系。虽然不是调解人,但药物的使用与依从性显着相关。总体而言,这项研究支持艾滋病毒的耻辱感与抗逆转录病毒疗法依从性之间的显着关系。这些发现使人们更加需要在设计旨在减少污名化的干预措施中包括艾滋病毒的污名化。这项研究支持的艾滋病毒柱头与抗逆转录病毒治疗依从性之间的直接关系表明,有必要研究可能影响抗逆转录病毒依从性的其他远端心理社会因素。

著录项

  • 作者

    Lewis, Trevor F., II.;

  • 作者单位

    New York University.;

  • 授予单位 New York University.;
  • 学科 Social work.;Public health.;LGBTQ studies.;Gender studies.;Virology.
  • 学位 Ph.D.
  • 年度 2018
  • 页码 169 p.
  • 总页数 169
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

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