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A systematic review of economic evaluations for interventions of cardiovascular diseases.

机译：对心血管疾病干预措施的经济评估的系统综述。

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摘要

Background. Cardiovascular disease (CVD) exhibits the most striking public health significance due to its high prevalence and mortality as well as huge economic burdens all over the world, especially in industrialized countries. Major risk factors of CVDs have been the targets of population-wide prevention in the United States. Economic evaluations provide structured information in regard to the efficiency of resource utilization which can inform decisions of resource allocation. The main purpose of this review is to investigate the pattern of study design of economic evaluations for interventions of CVDs.;Methods. Primary journal articles published during 2003-2008 were systematically retrieved via relevant keywords from Medline, NHS Economic Evaluation Database (NHS EED) and EBSCO Academic Search Complete. Only full economic evaluations for narrowly defined CVD interventions were included for this review. The methodological data of interest were extracted from the eligible articles and reorganized in Microsoft Access database. Chi-square tests in SPSS were used to analyze the associations between pairs of categorical data.;Results. One hundred and twenty eligible articles were reviewed after two steps of literature selection with explicit inclusion and exclusion criteria. Descriptive statistics were reported regarding the evaluated interventions, outcome measures, unit costing and cost reports. The chi-square test of the association between prevention level of intervention and category of time horizon showed no statistical significance. The chi-square test showed that sponsor type was significantly associated with whether new or standard intervention being concluded as more cost effective.;Conclusions. Tertiary prevention and medication interventions are the major interests for economic evaluators. The majority of the evaluations were claimed from either a provider's or a payer's perspective. Almost all evaluations adopted gross costing strategy for unit cost data rather than micro costing. EQ-5D is the most commonly used instrument for subjective outcome measurement. More than half of the evaluations used decision analytic modeling techniques. The lack of consistency in study design standards in published evaluations appears in several aspects. Prevention level of intervention is not likely to be a factor for evaluators to decide whether to design an evaluation in a lifetime horizon or not. Published evaluations sponsored by industry are more likely to conclude that new intervention is more cost effective than standard intervention.
机译：背景。心血管疾病（CVD）由于其高患病率和高死亡率以及世界各地特别是工业化国家的巨大经济负担而显示出最显着的公共卫生意义。 CVD的主要危险因素已成为美国人群预防的目标。经济评估提供了有关资源利用效率的结构化信息，可以为资源分配的决策提供依据。这篇综述的主要目的是研究针对CVD进行干预的经济评价研究设计模式。通过相关关键词从Medline，NHS经济评估数据库（NHS EED）和EBSCO Academic Search Complete中系统检索了2003-2008年发表的主要期刊文章。本文仅对狭窄的CVD干预措施进行了全面的经济评估。从符合条件的文章中提取了感兴趣的方法学数据，并在Microsoft Access数据库中进行了重组。 SPSS中的卡方检验用于分析分类数据对之间的关​​联。经过两步文献选择，并明确纳入和排除标准后，对120篇合格文章进行了审查。报告了有关评估干预措施，成果措施，单位成本和成本报告的描述性统计数据。卡方检验对干预预防水平与时间范围类别之间的关系无统计学意义。卡方检验表明，发起者的类型与是否得出新的或标准的干预措施更具成本效益显着相关。三级预防和药物干预是经济评估者的主要利益。大多数评估是从提供者或付款人的角度提出的。几乎所有评估都对单位成本数据采用总成本计算策略，而不是对微观成本进行计算。 EQ-5D是最常用的主观结果测量工具。超过一半的评估使用了决策分析建模技术。在已发表的评估中，研究设计标准缺乏一致性，这体现在几个方面。预防措施的干预程度不太可能成为评估人员决定是否在生命周期内进行评估的因素。由行业赞助的已发布的评估更有可能得出结论，即新的干预措施比标准的干预措施更具成本效益。

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  • 作者

    Zhang, Zhen.;

  • 作者单位

    The University of Texas School of Public Health.;

  • 授予单位 The University of Texas School of Public Health.;
  • 学科 Economics General.;Health Sciences Public Health.;Health Sciences Health Care Management.
  • 学位 M.P.H.
  • 年度 2009
  • 页码 53 p.
  • 总页数 53
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 经济学;预防医学、卫生学;预防医学、卫生学;
  • 关键词

  • 入库时间 2022-08-17 11:38:24

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