Objective To explore the clinical value of high frequency ultrasound in the differential diagnosis of benign and malignant thyroid nodules. Methods 100 cases of patients with thyroid nodules were selected as the study subjects. All patients were diagnosed by two-dimensional ultrasound and high frequency color Doppler ultrasound before operation, and the diagnosis was confirmed by pathology after operation. The differential diagnosis of benign and malignant thyroid nodules by high frequency ultrasound was compared with the pathological diagnosis, and the high frequency ultrasound imaging features were compared between benign and malignant nodules.ResultsIn 100 cases of patients, there were a total of 184 nodules. The sensitivity and specificity of high frequency color Doppler ultrasound were 91.89% and 88.16% respectively. There were signiifcant differences in morphology, boundary, acoustic halo, echo, calciifcation and blood lfow between benign and malignant thyroid nodules (P<0.01).Conclusion The sensitivity and specificity of high frequency ultrasound in the differential diagnosis of benign and malignant thyroid nodules are high, and the high frequency ultrasound imaging features of benign and malignant nodules are obvious, which can be used for clinical differential diagnosis.%目的探究高频超声在甲状腺良恶性结节鉴别诊断中的临床价值。方法选取100例甲状腺结节患者为研究对象，术前均行二维超声和高频彩色多普勒超声诊断，且术后经病理确诊。对比分析高频超声对甲状腺良恶性结节的鉴别诊断结果与病理诊断结果，并比较良恶性结节高频超声影像学特征差异。结果100例患者共计结节184个，高频彩色多普勒超声检查结果显示灵敏度为91.89%，特异度为88.16%。甲状腺良恶性结节与良性结节相比，在形态、边界、声晕、回声、钙化、血流方面，差异均具有统计学意义（P＜0.01）。结论高频超声对甲状腺良恶性结节的鉴别诊断灵敏度、特异度较高，且良恶性结节高频超声影像学特征明显，可用于临床鉴别诊断。
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