目的 探讨高龄非输卵管性不孕女性助孕治疗过程情绪障碍的影响因素.方法 回顾分析恩施土家族苗族自治州中心医院2015年10月～2017年5月收治的150例高龄非输卵管性不孕并采取助孕治疗患者的临床资料,根据抑郁自评量表(SDS)、焦虑自评量表(SAS)评估患者负性情绪,并根据结果分为正常组与情绪障碍组,分析两组女性患者临床资料,探讨其情绪障碍的影响因素.结果 150例患者中,出现情绪障碍者94例,情绪正常者56例;经单因素分析显示,情绪障碍组妇科炎症、性病、无业状态构成比依次是82.9％、14.8％、58.3％,均显著高于正常组的67.9％、3.5％、75.0％(P＜0.05),经济来源中仅男方、仅女方、男女双方共同承担的构成比依次是56.4％、39.4％、4.2％,与正常组的48.2％、25.0％、26.8％比较,差异有统计学意义(P＜0.05);情绪障碍组月经量异常率、月经紊乱、痛经史等发生率依次为79.8％、71.3％、90.4％,均显著高于正常组的62.5％、60.7％、75.0％,差异有统计学意义(P＜0.05);生化妊娠率、临床妊娠率依次为5.3％、4.3％,均显著低于正常组的16.1％、14.3％,差异有统计学意义(P＜0.05);多因素分析显示,妇科炎症、经济来源、职业状态、生化妊娠及临床妊娠情况均是高龄非输卵管性不孕女性情绪障碍的危险因素(P＜0.05).结论 高龄非输卵管性不孕女性助孕过程中易出现情绪障碍,其中生理情况、妇科炎症、经济收入等均是导致其产生负性情绪的诱发因素,在提供助孕服务时需注意防范.%Objective To explore the influencing factors of emotion disorders during assisted reproductive treatment in elderly women with non tubal infertility.Methods The clinical data of 150 cases of elderly non-tubal infertile women and given the assisted reproductive treatment in the Central Hospital of Enshi Autonomous Prefecture from October 2015 to May 2017 were retrospectively analyzed.The negative emotions were evaluated according to self-rating depression scale (SDS) and self-rating anxiety scale (SAS).According to the results,the patients were divided into the normal group and the emotional disorders group.The clinical data of the two groups were analyzed,and the influencing factors for their emotional disorders were explored.Results Among the 150 patients,there were 94 cases with mood disorders and 56 cases with normal mood.Univariate analysis showed that the proportions of gynecological inflammation,venereal diseases and unemployed status were 82.9％,14.8％ and 58.3％ respectively in the emotional disorders group,which were significantly higher than those in the normal group with 67.9％,3.5％ and 75.0％,the differences were statistically significant (P ＜ 0.05).And there were significant differences in the proportions of economic source from male,female and the combined male and female between the emotional disorders group and the normal group [(56.4％,39.4％,4.2％) vs (48.2％,25％,26.8％)] (P ＜ 0.05).The incidence rates of irregular menstruation,menstrual disorders and dysmenorrhea were 79.8％,71.3％ and 90.4％ in the emotional disorders group,which were significantly higher than those in the normal group with 62.5％,60.7％ and 75.0％,the differences were statistically significant (P ＜ 0.05).The biochemical pregnancy rate and clinical pregnancy rates were 5.3％ and 4.3％ respectively,which were significantly lower than those in the normal group with 16.1％ and 14.3％,the differences were statistically significant (P ＜ 0.05).Multivariate analysis showed that gynecological inflammation,economic sources,occupational status,biochemical pregnancy and clinical pregnancy were risk factors for emotional disorders in elderly women with non tubal infertility (P ＜ 0.05).Conclusion Emotional disorders are prone to occur during assisted reproductive treatment in elderly women with non tubal infertility,and the physiological conditions,gynecological inflammation and economic incomes are the inducing factors for negative emotion,and precautions should be taken in providing assisted reproductive services.
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